Test 2: Chapters 5-8 Flashcards
Neutrophil
Glandular; first to respond to infection
Phagocytes- eating cells
Sickle cell disease
Mutation caused misfolding of hemoglobin
Collapses RBCs to sickle cell shape; more likely to rupture
Pain, clotting, anemia
Eosinophil
Glandular; not sure of role, increase of numbers during allergy reaction
Worm infection
Basophil
Glandular; release histamine
Lymphocyte
Agrandular; responsible for specific immunity response
Monocyte
Agrandular; largest size; phagocytes
SCID: severe combined immunodeficiency disease
Missing enzyme leads to no lymphocytes
Cannot fight infections
Treat with injections or bone marrow transplant
Leukemia
Cancer of white blood cells
Overproduction but lack of function
Mononucleosis
Viral infection of lymphocytes
Remains in body for rest of life and can regenerate
Blood clotting
Steps to stop blood flow after damage
Constrict vessel
Plug hole
Ventricular systole
The ventricles contract and AV valves close while the SL valves open
Atrial Systole
Atria contract and ventricles relaxed and AV valves open
Atrium
Inflow
Left-from lungs
Right-from body
Pericardium
Fibrous sac in the heart
Systematic circuit
Oxygen rich blood is sent to the body and returns depleted
Left side of the heart
Aorta
Superior and inferior vena
Veins
Carry blood to heart
Venules
Smaller veins
Same 3 layers but much less muscle and connective tissue
Valves prevent back flow which can expand more
70% of blood in veins at one time
Atrioventricular
Between the atria and the ventricles
Atherosclerosis
The build up of plaque
Can lead to many clots
Increased blood pressure
Arterioles
Smaller arteries with less elastic tissue
Control of blood pressure
Homeostasis
Body’s ability to maintain constancy of internal environment
Maintained by negative feedback mechanisms
Cardiovascular system
Heart and blood vessels circulate blood around body in a continued loop
Heart contracts to generate movement
Vessels transport between body and heart
Lymphatic system helps by returning fluids to blood from tissues
Aneurysm
Ballooning of blood vessels
Harmful when it bursts
Leukocytes
White blood cells
Less than 1% blood volume
Immune system
Capillaries
Very small Site of exchange with tissues Only endothelium (very thin walls) Large branched networks or "beds" Control flow using pre capillary
Erythrocytes
Red blood cells
45% blood volume
Oxygen transport
Thrombocytes
Platelets
Less than 1% blood volume
Blood clotting
Stroke
When blood flow to brain is blocked core arteriole ruptures and part of the brain dies from lack of oxygen
Blood
Connective tissue with cellular elements suspended in liquid matrix
What are the functions of blood?
Transport- oxygen, nutrients, hormones, and wastes
Protection- immune system and clotting
Regulation- Ph and temperature
Myocardium
Cardiac muscle in the heart
Endocardium
Smooth lining layer to reduce friction in the heart
Pulmonary circuit
Oxygen poor blood sent to lungs and returns enriched
Right side of heart
Pulmonary artery and vein
Arteries
Carry blood away from heart
What are the 3 layers of the arteries?
Endothelium lining
Smooth muscle with elastic tissue
Connective tissue
Plasma
Straw colored liquid
55% of blood volume
Mostly water (91%)
Mainly solutes
What are the proteins of plasma?
Albumins- water balance
Globulins- transport and antibodies
Fibrinogen- clotting
Heart attack
When blood flow to heart is blocked and part of the muscle dies from lack of oxygen
Ventricle
Output
Left-to body
Right-to lungs
RBCs
Made in bone marrow
No nucleus when mature
Live 120 days(destroyed in liver and spleen)
Low platelet count
Bleeding, bruises, nosebleeds
Hemophilia
Genetic disorder where one clotting factor deficient
Bleeding never clots
Now treat with injections
Blood clots
Thrombus formation (stationary)
Embolus (moving)
Danger when blood flow is blocked
Blood types
Genetically determined
Glycoproteins on cell surface recognized as antigens in other bodies