Test 2 Flashcards
immunoglobulins are transferred from one person to another; (weeks or months);E: injections of exogenous immunoglobulins or from mother to infant via colostrum or placenta
passive immunity
person’s own immune system generates the immune response
active immunity
ability to destroy and remove an antigen from the body through antibodies
immunity ( immunologic memory )
vaccines mimic the characteristics of
an antigen
modified living organisms; replicate in the body but don’t cause disease
life attenuated vaccines - 1 or 2 doses
use whole dead organisms or pieces weaker antigen;
inactivated vaccines - require multiple doses
genetically engineered; E: hepatitis B vaccine
recombinant inactivated vaccine
updates vaccine schedules yearly;
• Advisory Committee on Immunization Practices (ACIP)
Vaccine storage and administration
package insert
must be provided to parents whose kids receive vaccine
Vaccine Information Statements (VIS) - whats for, side effects
Report any clinically significant adverse reaction
to the
Vaccine Adverse Event Reporting System
Proper documentation
date; name of vaccine; lot number and expiration date; manufactures name; site and route; name and address of the facility
DTaP
under 1
( diphtheria, tetanus, and pertussis ) ; for children under 7 ; first one - under 1; IM
Tdap
for children over 7; tetanus booster for older kids (11-12) every 5-10 years;
– Rising pertussis cases since 1970 - infants, adolescents and young adults.
Hib
under 1
Haemophilus influenzae Type B Vaccine; prevents – meningitis, epiglottitis, septic arthritis in children under age 5 ; IM
Polio vaccine
under 1
* polio - paralytic disease
– Inactivated polio vaccine (IPV)
currently recommended in US
– Killed virus, poses no risk of infection; SC - subcute
Hep B
under 1
Hepatitis B; – Recombinant vaccine
– Series usually started at birth before discharge from hospital; 3 doses in 6 months ; IM
Pneumococcal vaccine
under 1
– Streptococcus pneumoniae most common cause of serious
infection in children under age 2 - pneumonia, sepsis, meningitis, otitis media; – Conjugate vaccine (13 strains) started in infancy; IM
Rotavirus vaccine
under 1
– Most common cause of severe
gastroenteritis (infectious diarrhea) in young children
– Live vaccine, given by oral route to infants
MMR
over 1
Measles, Mumps, and Rubella Vaccine ; – Live attenuated virus combination
– 2 doses given to children > 12 months of age ( before kindergarten ) ; SC
Varicella vaccine
over 1
chicken pox ; – Live attenuated virus
– 2 doses given to children > 12 months of age; SC
Hep A
over 1
Hepatitis A vaccine; IM
– Inactivated whole virus vaccine
– One of the most frequently reported diseases in the US
– 2 doses given to children > 12 months of age ( 12-15 month and 2nd - 6 month later)
Meningococcal vaccine
age 11
IM; Neisseria meningitidis causes meningitis and sepsis
– 10-12% of infected persons die, 20% of survivors suffer longterm consequences; 11-12 - booster at age 16
HPV
11-12
Human Papillomavirus vaccine; IM; – Infection most common in adolescents and young adults who are sexually active
– HPV causes genital warts that can lead to cervical cancer; for girls only ; for boys and girls ( 3 shots )
Influenza vaccine
IM; – Universally recommended > 6 months of age; inactivated - IM; nasal mist - alive ( not for compromised children) ; intradermal injection - inactivated ( not for children under 18).
Mild common reactions to immunization
Fever - 102.9 ( OK); irritability; sleepiness; poor appetite; rash ( MMR and varicella) - 5-20 days
Severe - concorning ( rare) reactions
difficulty breathing ( allergic reaction ) - pallor, weakness, decreased BP, hives ; seizures ; after DTaP - crying for 3 hours ( increased irritability)
Post-Vaccine Interventions
• Tylenol every 4 hours for pain or fever
• No ibuprofen to infants < than 6 months of age
• No ASA to any child under 16 years of age
• Warm baths or compresses
• Encourage ambulation or use of affected
extremity
Immunize - yes
- Child is on antibiotics;
- Minor illness - except flue vaccine
- Mild allergies
- Breastfeeding infant and parent
- Pregnant household contact
- Allergy to eggs - except flue (influenza) vaccine
Immunize - NO
- rash or hives after previous injection
Barriers to Immunization
- Parental concerns re: safety
- Misconceptions - autism ? thimerosal ( mercury ) ?
- More than 1 health care provider
- Multiple children in family
- Cost
- Concern about multiple vaccines
Overcoming Barriers
• Combination vaccines - reduce the number child gets sticked
• Vaccines for Children (VFC) program
implemented in 1994 - can get it at medical home from goverment
• Establish medical home
• Verify immunization status at every visit
• Verify status of siblings accompanying child
• Maintain centralized record
Differences in the skin
skin is thinner; blood vessels closer to the body ; heat loss more readily; substance absorbed more readily; more water, less pigment - risk for sun damage
Physical examination of skin
note temperature, moisture, texture; describe lesions: appearance- macular (flat); papular (bumpy); vesicular (blisters); pustular( with puss); shape: round; oval; annular( central clearing); linear; target rash (bull’s eye) ; drainage: clear, purulent; honey color; or otherwise; note scaling, lichenification (thickening); tattoos, piercing.