Test 2 Flashcards
HSV1
Perioral lesion, UV exposure causes lesion, young= gingivostomatitis, old= pharyngotonsilitis (sore throat, fever, headache). resides in trigeminal ganglion (latency). Prodrome 6-24 hours (tingling that is viral replication), 2d it crusts, 7-10 days it resolves. ALWAYS on keratinized bound mucosa. Test takes 4-8 hours. Attached gingiva
HSV2
sensory ganglion, same as HSV1
HSV3
varicella-zoster: chickenpox is primary, herpes zoster is recurrent. Latent in dorsal spinal ganglion, occurs in 20% of people (usually older), usually 1 recurrence (stress, alcohol, abuse, immune weakening). Movable or bound tissue, if tip of nose is involved send to opthomalogist, Ramsay Hunt syndrome. Respiratory or contact spread
ramsay-hunt syndrome
external auditory herpes infectio, ipsilateral face paralyisis, veritgo, hearing defect
HSV4
Epstein Barr: Mononucleosis: Fatigue, malaise, anorexia. Dx= paul-bunnel heterophile antibodies, 4-6 weeks of pain pills, and sometimes abx. Also seen in oral hairy leukoplakia (bilateral), lymphomas (Africans burkitt), nasopharyngeal carcinoma.
Hsv5
cytomegalovirus: Salivary glands, endothelium, macrophages, lymphocytes. 90% asymptomatic. Fever, arthralgia, muscle pain, and shivering. Common in AIDS, chronic mucosal ulcerations, “owl eye”
HSV8
Karposis Sarcomma: multifocal neoplasm of vascular endothelial origin, 20% of AIDS, Hard palate, gingiva, tongue. Oral cavity can be primary site of involvement
shingles
chickenpox is primary, herpes zoster is recurrent. Latent in dorsal spinal ganglion, occurs in 20% of people (usually older), usually 1 recurrence (stress, alcohol, abuse, immune weakening). Movable or bound tissue, if tip of nose is involved send to opthomalogist, Ramsay Hunt syndrome. 1-4 mm white opaque vesicles that rupture to form shallow ulcerations
infectious mononucleosis
Epstein Barr: Mononucleosis: Fatigue, malaise, anorexia. Dx= paul-bunnel heterophile antibodies, 4-6 weeks of pain pills, and sometimes abx.
herpangina
coxsackie virus. 2-6 lesions in posterior mouth (soft palate/ tonsils). red macules that rapidly ulcerate. 3 mm in diameter, resolve in 10 days. Sore throat, fever, dysphagia.
hand-foot disease
Coxsackie virus: Flu like symptoms. 30 lesions up to 1 cm in diameter. Buccal, labial, and tongue, peripheral ulcers develop after oral (foot and hand) heal without crusting
rubeola- measles
): paramyxovirus: winter, respiratory droplets. 10-12 days of incubation. 9 day course of three stages. 1 stage: cough, coryza, conjunctivitis, kopliks spots. 2 Stage: fever, kopliks fade, rash (face then down). 3rd stage: healing
rubella
Togavirus. Congenital (hearing defects, heart defects, cataracts) rash, arthritis, forchiemers sign (small, dark, red papules on palate) 2-3 wks incubation. Contagious from 1 wk before rash to 5 days after.
mumps
disease of exocrine glands (salivary glands). Edema and lymphocytic infiltration. 2-4 wk incubation. Discomfort/swelling, salivation is painful. Epididymorchitis.
HIV
Bodily fluids, targets CD4+. Candidiasis( clotrimazole or systemic fluconazole if not on HAART), hairy leukoplakia (on border of tongue), karposis sarcoma (20% of AIDS, 70% of KS have oral lesions), non hodgkins, periodontal disease (linear gingival erythema , nup, nug) haart drops down chance of exposure by 75%. .3 for puncture .09 for mucus membrane
kaposis sarcomma
multifocal neoplasm of vascular endothelial origin, 20% of AIDS, Hard palate, gingiva, tongue. Oral cavity can be primary site of involvement. 70% have oral lesion
linea alba
White Line, sucking, chewing, trauma. Bilateral. 10% of population
moriscatioa buccarum
chronic cheek chewing/trauma. Linguarum, labiorum. Stress plays a role
thermal burns
food or beverage. Usually on palate/ posterior buccal mucosa. Erythema and ulceration
bronj
inhibit osteoclast. Possibly interfere with angiogenesis. Second generation has nitrogen side chain and 10 year half life. Medication goes to highest area of remodeling (jaw) bigger deal in mandible (more dense and less blood supply) 6-8% FOR iv bisphosphonates, 1:100,000 for PO. 60% occur after dental procedure 40% is spontaneous. PO you need written consent, IV avoid manipulation.
meth
parasitosis (snakes, insect crawling around mouth). Dries out the mouth and sugary snacks cause caries. Smooth surface and root. Affect sympathetic amines for 6 hours (hypertensive crisis, CVA, MI)
amalgam tattoo
amalgam gets implanted into mucosa. Dx by radiograph. Blue, black, grey. If cant see on radiograph biopsy.
smokers melanosis
nicotine stimulates melanin production. 20% of smokers (3% of non smokers) cessation of smoking has gradual disappearance. Cut out what remains after 6 weeks. If unusual looking or in unusual place, biopsy
antral psuedocyst
Pano, dome shaped, slightly RO lesion on floor of maxillary sinus. Exudate/ serum glob of inflam cells cause sessile elevation. 2-15% of population.
recurrant apthous ulcers
RAU- much more painful than appear- canker sore- only on movable mucosa. Minor Major Herpetiform Size 3-10 mm 10-30 mm 1-3mm Healing time 1-2 weeks 2-6 weeks 7-10 days Scarring No Possible No Lesions 1-5 1-10 100 Recurrances Few Medium Most (can be continuous) Age Child Adolescent adult
behcets syndrome
chronic recurrent immune mediated disease with oral apthous –like ulcers (can be on fixed mucosa). Ocular inflammation, joint inflammation, genital ulcers, skin lesions. Tx steroids
sarcoidosis
multisystem granulomatous disease of unknown cause. Lungs, lymph (almost always), skin, eyes, salivary glands. Skin Lesions = lupis pernio (chronic, purple, indurated, leasions on H&N) and erythema nodosum (scattered, nonspecific, swollen red nodules on lower legs- swollen fat deposits). DX: elevated serum angiotensin-converting enzyme levels
lofgrens syndrome
erythema nodosum, bilateral hilar lymphadenopathy, althralgia