Test 2 Flashcards
F protein
Strep
Adhesion and evasion of epithelial cells
Capsule
Strep
inhibits phagocytosis
Lipoteichoic Acid
Strep
adhesion to epithelial cells
M-like proteins
Strep
inactivate IgM and IgG
inhibit protease
no antibodies form against them
Enterotoxin C & D
Contaminated milk
Exfoliative toxins
Staph - CPS
Cause SSSS and Bullous Impetigo
Breaks proteins that bind cells together
Streptokinase
Strep
Convert plasminogen to plasmin
plasmin breaks down colts
infection spreads better
Streptolysin O
Strep
Oxygen liable
Immunogenic
Streptolysin S
Strep
Oxygen stable (S)
Serum dependent
NON-immunogenic
Alpha toxin
Staph - CPS
heat stable
disrupt membrane —> lysis
Diseases treated by broad spectrum penicillins and cephalosporins
Group A strep of allergic to Penicillin G
Strep pneumoniae - pneumonia and bacteremia
CPS - SSSS, Impetigo, acute endocarditis
CNS
Beta toxin
Staph - CPS
Heat liable
works with alpha toxin
Delta toxin
Staph
Heat stable
Detergent
enterotoxin
Staph
Heat stable
Resist digestive enzymes
peptidoglycan
Staph - CPS & CNS
endotoxin
induces fever
Diseases treated by narrow spectrum penicillins
Group A strep
Group B strep
Acute Endocarditis caused by CPS
Subacute endocarditis caused by CNS
Enterotoxin A
Food poisoning
Enterotoxin B
Enterocolitis
Diseases treated by chloramphenicol
Strep pneumoniae - meningitis
Diseases treated by sulfonamides
CNS - UTIs
TSST
Staph - CPS
Heat stable
resist digestive enzymes
can penetrate and go systemic
Diseases treated by macrolides
Group A strep if allergic to Penicillin G
Strep pneumoniae - pneumonia and bacteremia
CNS - subacute endocarditis
What are the diseases only caused by lysogenic strains?
Scarlet Fever
Strep TSS
SSSS - Staphylococcal Scalded Skin Syndrome
Staph Impetigo
Describe each of the 5 periods of disease.
Incubation - The period between infection and first signs
Prodromal - first mild symptoms appear
Illness - Diagnostic s/s symptoms, immune response highest
Decline - Symptoms subside
Convalescence - Actively gain strength and return to health