test 2 Flashcards
what are the four main sources of topics?
- theory
- personal experience
- replication
- literature and previous studies
what is a theory?
organised body of concepts/generalisation/principles subjected to investigation
what are three problems with broad topics?
- enlarges scope beyond reason
- complicates organisation of review
- too general, difficult to carry out/interpret
what are some suggestions that can narrow topics?
talking to experts and read secondary sources that provide overviews
how do quant and qual studies differ when the topic is narrowed?
quant tend to narrow topic initially and qual narrow throughout
what are some factors that make a topic researchable?
- can be investigated throughout collection and analysis of data
- theoretical or practical
- contribute to educational process
- ethical
what are some factors that make a topic non-researchable?
-matters of opinion
what does a formal statement of quant research topic involve?
- identifies variable of interest
- describes specific relationship between variables
- identifies nature of participants
what are some functions of a literature review?
- determine what has been done
- provide insight to develop framework into which topic fits
- identifies useful methodological strategies
- facilitates interpretation of results
what is a literature review?
involves systemic identification, location and analysis of documents containing info related to research problem for question
what are some general recommendations for the scope of a literature review?
- bigger isn’t better
- heavily researched topics provide references to focus only o major studies
- lesser researcher require reviewing any study related in meaningful way
what are the four stages when conducting a lit review?
- identify keywords
- identify sources
- abstracting info founding references
- analysing, organising, and reporting lit
what are the seven steps of locating, reviewing, summarising, and classifying references in lit reviews?
- read abstract
- skim article
- record complete bibliographic info
- classify/code article
- summarise
- identify thoughts about what is important
- indicate direct quotes properly
what are the characteristics of sources in lit reviews?
- primary and secondary
- empirical and opinion
what are the two characteristics of meta-analysis?
- review as inclusive as possible
- results of each study are translated into stat called effect size
what is an effect size in a meta-analysis?
difference between means for experimental and control in CG standard deviation units
what does the average of all effect sizes summarising in meta-analysis?
summarises overall effect of studies
what is an inductive view of hypotheses?
generalisation made from number of observations (qual)
what is a deductive view of hypotheses?
derived from theory aim at providing evidence to support/expand/contradict (quant)
what is a good hypothesis?
- based on reasoning
- provides reasonable explanation for predicted outcome
- clearly states expected relationships between variables
- testable
what is a non-directional type of quant hypothesis?
statement that no relationship or difference exists between variables
what is a directional type of quant hypothesis?
statement of expected direction of relationship/difference between variables
what is a null type of quant hypothesis?
stat statement that no statistically significant relationship/difference exists between variables
how are hypothesis tested?
- stat analysis of data
- importance of results regardless of outcome
- results support or fail to support hypotheses, never disprove or prove
what does writing a lit review involve?
- report primarily on original sources of scholarship
- gives justification
- provide background
- describes, summarises, evaluates, compares and integrates content of primary reports
what are some reasons for lit reviews?
- identify gaps
- avoid repeating mistakes
- build on other’s work
- increase breadth of knowledge
- identify people in same field
what is a systemic review?
lit review focused on single question which tries to identify, appraise, and synthesise high quality evidence relevant to question
what is a meta-analysis?
statistical technique often used in systemic reviews enabling results from no.of quant studies combined into common metric to determine average effect of technique
what is an integrative review?
lit review that attempts to combine experimental and non-experimental studies
what can integrative reviews be used for?
review theories, evidence, or to analyse methodological issues
what is a qualitative review?
methods for combining qual studies, techniques include meta-synthesis, formal grounded theory and meta-ethnography
why do we use systemic reviews?
- minimise impact of bias/errors
- end confusion
- highlight findings from different studies
- can mitigate need for further trials
what is the significance of systemic reviews?
large amount of medical lit requires clinicians/researcher are likely to rely on one systemic review to make informed decisions
why are systemic reviews necessary?
volume of material makes it impractical for clinician to remain up to date
what are the benefits of systemic reviews?
- detect small but significant treatment effects
- save time/money
- clear method and results
- define boundary of what is known and not
who can undertake systemic reviews?
- cochrane/campbell collabs
- regulatory bodies
- academics
- health tech assessment
- multidisciplinary teams
what are some key characteristics of systemic reviews?
- clearly stated title/objective
- explicit criteria for inclusion/exclusion
- presentation of characteristics of each study and analysis of method quality
what are some steps in the process of conducting a systemic review?
- define review questions
- develop protocol
- identify relevant studies
- assess eligibility
- extract data
- critically appraise
- synthesise
- disseminate
what will a well-formulated review question encompass?
- search strategy
- inclusion/exclusion
- data extraction
- choice of synthesis method
- presentation/dissemination of findings
what are some challenges to lit search?
- database bias
- publication bias
- english language bias
- citation bias
when does citation bias occur?
when studies with significant or positive results are referenced on other republications, compared with studies with inconclusive or neg findings
what are the three broad categories of critical appraisal of qual studies?
- rigour: thorough and appropriate approach been applied to key methods
- credibility
- relevance
what are some methods for quant data synthesis?
meta-analysis and narrative synthesis
what are some methods for qual data synthesis?
methods depending on review purposes eg. meta-ethnography, thematic synthesis
what is a meta-analysis?
set of stat techniques for combining results from independent but similar to derive an overall estimate of treatments effect
what are some potential issues of meta-analysis?
publication bias and varying quality of studies
what are the two statistical models of analysing data used?
fixed and random effects
what is the fixed effect as a stat model to analyse data?
assumes that true effect of treatment is the same for every study
what is the random effect as a stat model to analyse data?
assumes that true effect estimate for each study vary
what are integrative reviews?
provide review of available lit according too clear methodological approach
what are some potential sources of bias for integrative reviews?
- incomplete lit search strategy
- errors in data extraction
- inappropriate data analysis
what are some lit search issues in integrative reviews?
- obtaining needed lit often challenging
- publication bias
- identify max no.of primary sources through multiple strategies
what are some data evaluation issues in integrative reviews?
- explicit assessment of study quality
- how to define quality of non-empirical studies
what are some major types of qualitative research?
- participant observation
- interview
- record review
- focus groups
- case studies
what are some stages of qual evidence synthesis?
- formulate questions
- conduct systemic lit search
- screen/select appropriate research articles
- analysing findings
- maintaining quality control
- present findings
what are some underlying assumptions of qual research?
- expect more from meta-synthesis than single
- findings that make-up a MS database have already bee saturated
- redundant saturation of exisiting findings
- priority is to synthesise more info
what is the relationship of stats to clinical practice?
- hypothesis generated
- research plan devised of study effects of treatment method
- quantifiable data collected
- results interpreted
- conclusions drawn/shared
what is the null hypothesis?
statement of no difference between/among participants
what is the alternate hypothesis?
statement that there is a definite difference among participants
what is statistical analysis concerned with?
organisation/interpretation of data according to well defined, systemic procedures
what are the 4 levels of stat analysis?
- descriptive
- inferential
- associational
- difference
what is descriptive stats as a level of analysis?
data reduction, reduces large sets into interpretable forms
what is inferential stats as a level of analysis?
inference to known population from findings in sample
what is associational stats as a level of analysis?
causality refers to set of procedures to identify relationships between multiple variables
what is the difference as a level of analysis?
determining the difference between two groups or sets of data.
what are some types of descriptive stats?
- measures of central tendency
- measures of variability
- bar graphs
- histograms
- bivariate descriptive stats
- scatter diagrams
what are some measures of central tendency?
mode, median and mean
what are measures of variability?
- range
- interquartile range
- sum of squares
- variance
- standard deviation
what are bivariate descriptive stat types?
contingency tables and correlational analysis