test Flashcards

1
Q

a symptom indicative of angina is chest pain that typically ___?

A

lasts for several minutes

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2
Q

how does GTN primarily reduce preload?

A

relaxing veins

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3
Q

what is the first stage of Leventhal et al’s common sense or self-regulatory model?

A

primary appraisal

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4
Q

what is the psychological component of a comprehensive cardiac rehabilitation programme that is best supported by evidence?

A

CBT

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5
Q

familial hypercholesterolemia is primarily due to the production of defective what?

A

LDL receptors

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6
Q

LDL is retained within the vessel wall by interacting primarily with what?

A

proteoglycans

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7
Q

what receptors on macrophages can oxidised LDL interact with?

A

SR-A or CD36

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8
Q

what is P-selectin?

A

a protein produced by activated platelets and endothelial cells that functions as a cell adhesion molecules

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9
Q

what is ICAM-1?

A

(AKA CD54) — a transmembrane GP that plays a role in inflammatory processes and in the T-cell mediated host defence system

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10
Q

what ion is responsible for vasodilatory control of local blood flow regulation?

A

K+

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11
Q

what do secondary signals do after an increased frequency of nerve impulses from baroreceptors have entered the tractus solitarius?

A

inhibit the vasoconstrictor centre of the medulla

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12
Q

what would be decreased by a drug that increases the radius of resistance vessels?

A

capillary blood flow

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13
Q

what is pulmonary artery systolic pressure typically? diastolic? venous?

A
15-30mmHg = systolic
4-10mmHg = diastolic 
2-15mmHg = pulmonary venous/pulmonary capillary wedge pressure
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14
Q

what is the normal pressure range for LV systolic and diastolic pressures?

A
systolic = 100-140mmHg
diastolic = 3-12mmHg
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15
Q

postural hypotension is the main adverse effect of what class of anti-hypertensive drug?

A

a1-blockers

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16
Q

what do ACE inhibitors increase?

A

salt excretion

17
Q

what is the normal site of haematopoiesis in an infant?

A

bone marrow in all bones

18
Q

name 4 substances that aid platelet aggregation?

A
  • ADP
  • platelet derived GF
  • serotonin
  • TXA2

not prostacyclin

19
Q

what is factor VIII(a) a co-factor of?

A

factor IX

20
Q

what is an intrapersonal factor that would influence altruism and likelihood of helping?

A

prejudice

21
Q

what clotting factor is NOT produced in the liver?

A

III

22
Q

what protein do thrombolytic drugs most commonly activate?

A

plasminogen

23
Q

the mechanism of aspirin’s anticoagulant effect relies on the fact that after blocking the COX enzyme what is the result?

A

platelets cannot synthesise TXA2

24
Q

There is a positive correlation between pulse pressure and cardiac output (CO). What statistical method might be used to predict an individual’s CO if their pulse pressure was known?

A

linear regression

25
Q

a person’s future participation in an exercise programme is best predicted by what?

A

their past participation in exercise

26
Q

what is the major adverse outcome of compartment syndrome?

A

ischaemia

27
Q

hypovolaemic shock would be expected to alter cardiac activity to produce what?

A

tachycardia

28
Q

the layer of dense connective tissue surrounding a muscle or groups of muscle (fascia) is mainly composed of what?

A

collagen

29
Q

the pulmonary wedge capillary pressure serves as an indirect measure of pressure in where?

A

left atrium

30
Q

what is the null hypothesis when conducting the Shapiro-Wilk test?

A

the sample was drawn from a normally distributed population

31
Q

what blood groups are X, Y, Z?

A
X = B
Y = A
Z = AB
32
Q

What substance released from vascular endothelial cells facilitates adherence of platelets to collagen?

A

vWF

33
Q

where is the moderator band?

A

RV

34
Q

which blood vessel receives blood from the chamber with the thickest compact myocardium?

A

ascending aorta

35
Q

Which blood vessel delivers blood to right side of the head and neck and upper limb?

A

brachiocephalic trunk