test Flashcards
a symptom indicative of angina is chest pain that typically ___?
lasts for several minutes
how does GTN primarily reduce preload?
relaxing veins
what is the first stage of Leventhal et al’s common sense or self-regulatory model?
primary appraisal
what is the psychological component of a comprehensive cardiac rehabilitation programme that is best supported by evidence?
CBT
familial hypercholesterolemia is primarily due to the production of defective what?
LDL receptors
LDL is retained within the vessel wall by interacting primarily with what?
proteoglycans
what receptors on macrophages can oxidised LDL interact with?
SR-A or CD36
what is P-selectin?
a protein produced by activated platelets and endothelial cells that functions as a cell adhesion molecules
what is ICAM-1?
(AKA CD54) — a transmembrane GP that plays a role in inflammatory processes and in the T-cell mediated host defence system
what ion is responsible for vasodilatory control of local blood flow regulation?
K+
what do secondary signals do after an increased frequency of nerve impulses from baroreceptors have entered the tractus solitarius?
inhibit the vasoconstrictor centre of the medulla
what would be decreased by a drug that increases the radius of resistance vessels?
capillary blood flow
what is pulmonary artery systolic pressure typically? diastolic? venous?
15-30mmHg = systolic 4-10mmHg = diastolic 2-15mmHg = pulmonary venous/pulmonary capillary wedge pressure
what is the normal pressure range for LV systolic and diastolic pressures?
systolic = 100-140mmHg diastolic = 3-12mmHg
postural hypotension is the main adverse effect of what class of anti-hypertensive drug?
a1-blockers