Test 1 (Renal/Hematological) Flashcards

1
Q

What is needed to make RBC’s?

A
Iron
Vitamin b12
Folate
Bone marrow tissue
Erythropoietin
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2
Q

Normal WBC count

A

5,000-10,000

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3
Q

A WBC count greater than 10,000 means

leukocytosis

A

Inflammation or infection

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4
Q

A WBC count less than 5,000 means

leukopenia

A

Immune compromised

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5
Q

Normal platelet count

A

150,000-450,000

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6
Q

Plasma is made of

A

water
sugar
protein
albumin

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7
Q

What medication is used to treat and prevent polycythemia?

A

Hydroxurea

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8
Q

What occurs in polycythemia?

A
Transport of RBC's slows down
Viscosity increases
Ruby red color
High risk for DVT
May have excess Ca+
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9
Q

What disease destroys RBC’s

A

Malaria and receiving the wrong Rh factor

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10
Q

Iron deficiency anemia

A

Result when the dietary intake of iron is inadequate for hgb synthesis

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11
Q

Most common cause of iron deficiency anemia in men and post menopausal women is

A

Bleeding (ulcers, gastritis, or GI tumors)

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12
Q

Most common cause of iron deficiency anemia in pre menopausal women is

A

menorrhagia and pregnancy with inadequate iron supplementation

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13
Q

S/S of anemia

A
Fatigue
Malaise
Pallor
Weakness 
Dyspnea
Tachycardia
Dizziness 
Orthopnea
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14
Q

A person with iron deficiency anemia may have what kind of tongue?

A

Smooth, sore and red

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15
Q

How to take oral iron supplements

A

Increase vitamin C intake
Take on empty stomach
Antacids/dairy products should be avoided
Drink liquid solutions thru straw

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16
Q

S/E of iron supplements

A

Constipation
Cramping
N/V
Dark green/black stools

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17
Q

What is aplastic anemia?

A

Bone marrow is replaced by fat. Most cases are idiopathic

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18
Q

What is the treatment for aplastic anemia?

A

Bone marrow transplant

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19
Q

S/S of aplastic anemia

A
Fatigue
Pallor
Purpura 
Dyspnea
Weakness
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20
Q

Aplastic anemia can be manged with immunosuppressive therapy commonly using

A

Cyclosporine

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21
Q

Antihemocyte globulin (ATG)

A

Removes the immunologic function that prolongs anemia and allows bone marrow to recover

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22
Q

Megaloblastic anemia is caused by

A

Deficiencies if vitamin B12 and folic acid

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23
Q

Nursing interventions for aplastic anemia

A

Observe for tissue hypoxia/bleeding
Good oral hygiene
No IM or SC injections

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24
Q

Neurologic manifestations occur in which kind of anemia

A

Vitamin B12 deficiency

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25
S/S of folic acid and vitamin b 12 deficiency anemia
Extremely pale Paresthesia in extremities Difficulty maintaining balance Proprioception
26
What is the classic method of determining the cause of vitamin B12 deficiency
Schilling test
27
What is the Schilling test?
Oral dose of radioactive vitamin B12, followed by nonradioactive vit B12. If no radioactive is present in urine, the cause is GI malabsorption. If the radioactive is present in urine the cause is not ilieal disease or pernicious anemia
28
How is folic acid deficiency treated
Increase folic acid intake 1mg daily
29
Folic acid is administered IM only to people with
Malabsorption problems
30
Absence of intrinsic factor is treated by
Monthly IM injection of vitamin B12 for life
31
What can cause/trigger a sickle cell crisis?
``` Cold Dehydration Fatigue Menstruation ETOH Acidosis ```
32
Sickle cell is associated with
Tacycardia Cardiac murmurs Cardiomegaly
33
Patients with sickle cell anemia are susceptible to
``` infection pneumonia osteomyelitis leg ulcers priaprism ```
34
Painful sickle crisis commonly result from
Tissue hypoxia and necrosis due to inadequate blood flow to a specific region or tissue or organ
35
Aplastic crisis results from
infection with the human parovirus
36
Treatment for sickle cell crisis is
HOP: hydration, oxygen, pain management
37
Pain meds used to relieve pain during crisis
Aspirin (mild/moderate pain, inflammation) NSAIDS (moderate pain) Morphine (most common for acute)
38
Hemophilia is a genetic defect caused by
A deficiency in factor 8 or 9, manifested by hemorrhage into various body parts. X-linked traits. almost all affected people are males
39
Most of the bleeding in pts with hemophilia occurs into
Joints (knees, elbow, ankles, shoulders, wrist and hips)
40
Other s/s of hemophilia include
Spontaneous hematuria and GI bleeding Coffee colored emesis Cola colored urine Tarry stools
41
Nursing interventions for patients with hemophilia
``` Avoid IM and SC injection Avoid aspirin, NSAIDS, herbs and alcohol. Apply pressure to control bleeding Splints to immobilize joints Good oral hygiene ```
42
Heat is avoided during bleeding episodes because
It can accentuate bleeding
43
DIC can be triggered by
``` Sepsis Trauma Cancer Shock Abruptio placentae Toxins Allergic reactions ```
44
Patients with DIC bleed from
Mucous membranes Venipuncture sites GI and urinary tracts
45
Steps before beginning blood transfusion
``` Check Rx Order to type and cross pt Explain procedure to pt OBTAIN CONSENT Take baseline vitals Use a 18/20 guage needle Bring Y-tube (NS) ```
46
Why cant dextrose be used for blood transfusions?
It is hypertonic and will kill RBCs
47
When transfusing blood obtain blood from blood bank after
The IV line is started
48
After obtaining blood from blood bank what are the next steps to take
Start blood transfusion w/in 30min from blood bank Double check label with 2nd nurse Check blood for gas bubbles/ unusual color
49
What should the 2 nurses verify before starting blood transfusion?
``` Right pt Right blood type Right bag number Right unit number Expiration date ```
50
A blood transfusion should take no longer than
2-4hrs
51
A reaction to a blood transfusioncan occur
Within the first 15 min
52
During a blood transfusion, vital signs should be taken
Every 5 min for the first 15 min.
53
If multiple transfusions are being given, what medication should be given to prevent fluid overload?
Lasix
54
S/S of adverse reaction during a blood transfusion
``` Restlessness Hives N/V Torso or back pain SOB Flushing Hematuria Fever or chills ```
55
If a reaction occurs during a blood transfusion, what action should the nurse take?
Stop the transfusion immediately and notify HCP
56
A blood transfusion should not go over 4hrs because
It increases the risk for bacterial infection
57
Different reactions that can occur during a blood transfusion
``` Febrile Overload Anaphylaxis Hemolytic Septic (Infection) Allergic Shock Acute lung injury Disease acquisition (Hep B and C, AIDS, CMV) ```
58
Causes of pre renal failure
``` Decreased CO Hemorrhage MI Sepsis HF Low BP ```
59
Causes of intra renal failure
``` NSAIDS Amino glycosides ACE inhibitors Metformin Trauma, burns ```
60
Causes of post renal failure
UTIs Kidney stones Tumors BPH
61
What are the four phases of ARF
Initiation Oliguric Diuresis Recovery
62
What occurs in the oliguric phase
Lasts 8-15 days, urinary output is less than 400 ml/day. Metabolic acidosis, hyperkalemia, HTN, edema, N/V, BUN/creatinine increase. Decrease in pH, hypocalcemia, increase in specific gravity
63
What occurs in the diuresis phase?
Nephrons begin to recover, increase in urinary output. Decline in BUN and creatinine. Dehydration and hypotension may occur
64
Causes of chronic renal failure
DM, HTN, chronic urinary obstruction, autoimmune disorders
65
S/S of chronic RF
``` Same as acute Crackles Protein in urine Yellow/grey pallor SOB Hematuria ```
66
Nursing interventions for pts with RF
``` Monitor I/O Limit Na and fluid intake Weigh daily Monitor/diet low in K Administer HCO3 IV Administer lasix ABGs (metabolic acidosis) Cardiac monitor Monitor BP/ give anti HTN Give Ca Kayaxelate ```
67
What is used to treat emergency hyperkalemia
Insulin or Ca gluconate
68
What can be prescribed to initiate diuresis
Mannitol or lasix
69
S/S of disequilibrium syndrome
``` Headache N/V Restlessness Decreased LOC Seizures ```
70
Nursing interventions for overload reaction during a transfusion
Stop transfusion NS to KVO Notify MD
71
What are s/s of over load reaction during a transfusion
``` Crackles SOB, JVD Increase in BP Flushed feeling Back pain Fever, chills Cyanosis ```
72
What are the nursing interventions during a febrile reaction during a transfusion
``` Stop transfusion NS to KVO Notify MD Call blood bank Return blood ```
73
What are the s/s of a febrile reaction during a transfusion
``` Flushed face Palpitations Cough Tightness of chest Increase in pulse Fever, chills ```
74
What are the nursing interventions for a septic reaction during a blood transfusion
``` Blood infused over 4 hrs Abnormal looking blood NS to KVO Stop transfusion Notify MD ```
75
What are the nursing interventions for a hemolytic reaction during a blood transfusion (donor and recipient incompatibility)
``` Most dangerous Stop transfusion IV colloids Mannitol Renal complications ```
76
S/S of a hemolytic reaction during a blood transfusion (acute)
General: Chills, Back/chest pain, Hemoglobinuria, anxiety Acute: Fever, increased HR, dyspnea, flank pain
77
S/S of a delayed hemolytic reaction
Increased anemia Increaed Billirubin Hemolysis
78
S/S of an air embolism during a blood transfusion reaction
Cyanosis Dyspnea Shock Cardiac arrest
79
S/S of a hypothermic reaction during a blood transfusion
Chills Decreased in body temp Peripheral vasoconstriction Cardiac arrest
80
What is BPH
The prostate increases in size. Cause is unknown. It extends into the bladder causing bladder outlet obstruction
81
What is TURP?
Common surgery for BPH, when the enlarged portion of the prostate is cut into pieces and removed thru the urethra by and endoscopic instrument.
82
S/S of an allergic reaction during a blood transfusion
HIves Generalized itching Flushing
83
S/S of a severe allergic reaction during a blood transfusion
Bronchospasm Laryngeal edema Shock