Test 1 (Renal/Hematological) Flashcards
What is needed to make RBC’s?
Iron Vitamin b12 Folate Bone marrow tissue Erythropoietin
Normal WBC count
5,000-10,000
A WBC count greater than 10,000 means
leukocytosis
Inflammation or infection
A WBC count less than 5,000 means
leukopenia
Immune compromised
Normal platelet count
150,000-450,000
Plasma is made of
water
sugar
protein
albumin
What medication is used to treat and prevent polycythemia?
Hydroxurea
What occurs in polycythemia?
Transport of RBC's slows down Viscosity increases Ruby red color High risk for DVT May have excess Ca+
What disease destroys RBC’s
Malaria and receiving the wrong Rh factor
Iron deficiency anemia
Result when the dietary intake of iron is inadequate for hgb synthesis
Most common cause of iron deficiency anemia in men and post menopausal women is
Bleeding (ulcers, gastritis, or GI tumors)
Most common cause of iron deficiency anemia in pre menopausal women is
menorrhagia and pregnancy with inadequate iron supplementation
S/S of anemia
Fatigue Malaise Pallor Weakness Dyspnea Tachycardia Dizziness Orthopnea
A person with iron deficiency anemia may have what kind of tongue?
Smooth, sore and red
How to take oral iron supplements
Increase vitamin C intake
Take on empty stomach
Antacids/dairy products should be avoided
Drink liquid solutions thru straw
S/E of iron supplements
Constipation
Cramping
N/V
Dark green/black stools
What is aplastic anemia?
Bone marrow is replaced by fat. Most cases are idiopathic
What is the treatment for aplastic anemia?
Bone marrow transplant
S/S of aplastic anemia
Fatigue Pallor Purpura Dyspnea Weakness
Aplastic anemia can be manged with immunosuppressive therapy commonly using
Cyclosporine
Antihemocyte globulin (ATG)
Removes the immunologic function that prolongs anemia and allows bone marrow to recover
Megaloblastic anemia is caused by
Deficiencies if vitamin B12 and folic acid
Nursing interventions for aplastic anemia
Observe for tissue hypoxia/bleeding
Good oral hygiene
No IM or SC injections
Neurologic manifestations occur in which kind of anemia
Vitamin B12 deficiency
S/S of folic acid and vitamin b 12 deficiency anemia
Extremely pale
Paresthesia in extremities
Difficulty maintaining balance
Proprioception
What is the classic method of determining the cause of vitamin B12 deficiency
Schilling test
What is the Schilling test?
Oral dose of radioactive vitamin B12, followed by nonradioactive vit B12. If no radioactive is present in urine, the cause is GI malabsorption. If the radioactive is present in urine the cause is not ilieal disease or pernicious anemia
How is folic acid deficiency treated
Increase folic acid intake 1mg daily
Folic acid is administered IM only to people with
Malabsorption problems
Absence of intrinsic factor is treated by
Monthly IM injection of vitamin B12 for life
What can cause/trigger a sickle cell crisis?
Cold Dehydration Fatigue Menstruation ETOH Acidosis
Sickle cell is associated with
Tacycardia
Cardiac murmurs
Cardiomegaly
Patients with sickle cell anemia are susceptible to
infection pneumonia osteomyelitis leg ulcers priaprism
Painful sickle crisis commonly result from
Tissue hypoxia and necrosis due to inadequate blood flow to a specific region or tissue or organ
Aplastic crisis results from
infection with the human parovirus
Treatment for sickle cell crisis is
HOP: hydration, oxygen, pain management
Pain meds used to relieve pain during crisis
Aspirin (mild/moderate pain, inflammation)
NSAIDS (moderate pain)
Morphine (most common for acute)
Hemophilia is a genetic defect caused by
A deficiency in factor 8 or 9, manifested by hemorrhage into various body parts. X-linked traits. almost all affected people are males
Most of the bleeding in pts with hemophilia occurs into
Joints (knees, elbow, ankles, shoulders, wrist and hips)
Other s/s of hemophilia include
Spontaneous hematuria and GI bleeding
Coffee colored emesis
Cola colored urine
Tarry stools
Nursing interventions for patients with hemophilia
Avoid IM and SC injection Avoid aspirin, NSAIDS, herbs and alcohol. Apply pressure to control bleeding Splints to immobilize joints Good oral hygiene
Heat is avoided during bleeding episodes because
It can accentuate bleeding
DIC can be triggered by
Sepsis Trauma Cancer Shock Abruptio placentae Toxins Allergic reactions
Patients with DIC bleed from
Mucous membranes
Venipuncture sites
GI and urinary tracts
Steps before beginning blood transfusion
Check Rx Order to type and cross pt Explain procedure to pt OBTAIN CONSENT Take baseline vitals Use a 18/20 guage needle Bring Y-tube (NS)
Why cant dextrose be used for blood transfusions?
It is hypertonic and will kill RBCs
When transfusing blood obtain blood from blood bank after
The IV line is started
After obtaining blood from blood bank what are the next steps to take
Start blood transfusion w/in 30min from blood bank
Double check label with 2nd nurse
Check blood for gas bubbles/ unusual color
What should the 2 nurses verify before starting blood transfusion?
Right pt Right blood type Right bag number Right unit number Expiration date
A blood transfusion should take no longer than
2-4hrs
A reaction to a blood transfusioncan occur
Within the first 15 min
During a blood transfusion, vital signs should be taken
Every 5 min for the first 15 min.
If multiple transfusions are being given, what medication should be given to prevent fluid overload?
Lasix
S/S of adverse reaction during a blood transfusion
Restlessness Hives N/V Torso or back pain SOB Flushing Hematuria Fever or chills
If a reaction occurs during a blood transfusion, what action should the nurse take?
Stop the transfusion immediately and notify HCP
A blood transfusion should not go over 4hrs because
It increases the risk for bacterial infection
Different reactions that can occur during a blood transfusion
Febrile Overload Anaphylaxis Hemolytic Septic (Infection) Allergic Shock Acute lung injury Disease acquisition (Hep B and C, AIDS, CMV)
Causes of pre renal failure
Decreased CO Hemorrhage MI Sepsis HF Low BP
Causes of intra renal failure
NSAIDS Amino glycosides ACE inhibitors Metformin Trauma, burns
Causes of post renal failure
UTIs
Kidney stones
Tumors
BPH
What are the four phases of ARF
Initiation
Oliguric
Diuresis
Recovery
What occurs in the oliguric phase
Lasts 8-15 days, urinary output is less than 400 ml/day. Metabolic acidosis, hyperkalemia, HTN, edema, N/V, BUN/creatinine increase. Decrease in pH, hypocalcemia, increase in specific gravity
What occurs in the diuresis phase?
Nephrons begin to recover, increase in urinary output. Decline in BUN and creatinine. Dehydration and hypotension may occur
Causes of chronic renal failure
DM, HTN, chronic urinary obstruction, autoimmune disorders
S/S of chronic RF
Same as acute Crackles Protein in urine Yellow/grey pallor SOB Hematuria
Nursing interventions for pts with RF
Monitor I/O Limit Na and fluid intake Weigh daily Monitor/diet low in K Administer HCO3 IV Administer lasix ABGs (metabolic acidosis) Cardiac monitor Monitor BP/ give anti HTN Give Ca Kayaxelate
What is used to treat emergency hyperkalemia
Insulin or Ca gluconate
What can be prescribed to initiate diuresis
Mannitol or lasix
S/S of disequilibrium syndrome
Headache N/V Restlessness Decreased LOC Seizures
Nursing interventions for overload reaction during a transfusion
Stop transfusion
NS to KVO
Notify MD
What are s/s of over load reaction during a transfusion
Crackles SOB, JVD Increase in BP Flushed feeling Back pain Fever, chills Cyanosis
What are the nursing interventions during a febrile reaction during a transfusion
Stop transfusion NS to KVO Notify MD Call blood bank Return blood
What are the s/s of a febrile reaction during a transfusion
Flushed face Palpitations Cough Tightness of chest Increase in pulse Fever, chills
What are the nursing interventions for a septic reaction during a blood transfusion
Blood infused over 4 hrs Abnormal looking blood NS to KVO Stop transfusion Notify MD
What are the nursing interventions for a hemolytic reaction during a blood transfusion (donor and recipient incompatibility)
Most dangerous Stop transfusion IV colloids Mannitol Renal complications
S/S of a hemolytic reaction during a blood transfusion (acute)
General: Chills, Back/chest pain, Hemoglobinuria, anxiety
Acute: Fever, increased HR, dyspnea, flank pain
S/S of a delayed hemolytic reaction
Increased anemia
Increaed Billirubin
Hemolysis
S/S of an air embolism during a blood transfusion reaction
Cyanosis
Dyspnea
Shock
Cardiac arrest
S/S of a hypothermic reaction during a blood transfusion
Chills
Decreased in body temp
Peripheral vasoconstriction
Cardiac arrest
What is BPH
The prostate increases in size. Cause is unknown. It extends into the bladder causing bladder outlet obstruction
What is TURP?
Common surgery for BPH, when the enlarged portion of the prostate is cut into pieces and removed thru the urethra by and endoscopic instrument.
S/S of an allergic reaction during a blood transfusion
HIves
Generalized itching
Flushing
S/S of a severe allergic reaction during a blood transfusion
Bronchospasm
Laryngeal edema
Shock