Test 1 Pretest

Question 0

The hydrophobic Effect  is known to be ? 
A) Exothermic
B) Decreasing entropy
C) Endergonic
D) Exergonic

Answer 0

D Exergonic

Question 1

chemical reactions are driving by?

A)temperature B) Entropy C) Concentration D) Enzymes

Answer 1

C Concentrations

Question 2

Gibbs free energy (delta ) is \_\_\_\_\_\_\_\_\_\_ on the path?
A) dependent
B) independent
C) interdependent
D) sometimes dependent

Answer 2

B) independant

Question 3

Which level of Protein structure is the last level where only a single polypeptide chain is present and what are the bonds that provide this structure
A) 2nd, Noncovalent interactions
B) 2nd, Hydrogen Bonds
C) 3rd, Hydrogen Bonds
D) 3rd, Hydrophobic interactions

Answer 3

D) Hydrophobic interactions

Question 4

Which A.A. has one less Hydrogen in its Backbone?
A) Tyrosine
B) Proline
C) Arginine
D) Tryptophan

Answer 4

B) Proline

Question 5

At physiological pH, generally speaking, a basic and acidic A.A. will respectively have what charge?
A) -, +
B) +, -
C) -, no charge
D) +, no charge

Answer 5

B) +, -

Question 6

Is it true/false that All Branched Chain A.A. are Essential?

Answer 6

True L I V

PVT TIM HALL

Question 7

Which A.A. is most likely found in Cartilage?
A) glycine
B) alanine
C) valine
D) lysine

Answer 7

A) Glycine

Question 8

Near Physiological pH, due to charges, A.A.'s are also called?
A) amphoteric
B) amphipathic
C) Ionic
D) Zwitterions

Answer 8

D) Zwitterions

Question 9

The formation of Amide bonds are done so in what direction and is this Favorable or unfavorable?
A) N to C Favorable
B) N to C Unfavorable
C) C to N Favorable
D) C to N Unfavorable

Answer 9

B

Question 10

The approx pKa of The N and C terminus on an A.A. is ?
A) 3 and 9
B) 2 and 8
C) 8 and 3
D) 10 and 2

Answer 10

C

Question 11

In columbs law, what does the D represent
A) Diversion const.
B) Density
C) Displacement
D) Dielectric const.

Answer 11

D

Question 12

Protein Structure is more Highly conserved than?
A) A.A. Sequence
B) Protein Subunit interaction
C) Protein Hydrogen bonding 
D) Protein Hydrophobic interactions

Answer 12

A

Question 13

What are bovine ribonuclease and human ribonuclease, if they carry out a similar function?
A) Homologs
B) Orthologs
C) Paralogs
D) Interlogs

Answer 13

B

Question 14

The Keratin Heptad has how many residues per turn?
A) 3.6
B) 3.5
C) 3.7
D) 1.8

Answer 14

B

Question 15

12 and 4  are the numbers of A.A. in what?  Respectively
A) Helix and Sheet
B) Helix and Strand
C) Sheet and Strand 
D) Sheet and Helix

Answer 15

B

Question 16

What two Fibrous Proteins provide structural support for the cells and tissues?
A) Collagen and Keratin (alpha and Beta)
B) Alpha Keratin and Beta Keratin
C) Collagen and Alpha Keratin
D) Collagen and Beta Keratin

Answer 16

C

Question 17

In Sheets and helices respectively, The H-bonds are in what orientation with the backbones?
A) Parallel and Perpindicular
B) Parallel and Parallel
C) Perpendicular and Perpendicular
D) Perpendicular and Parallel

Answer 17

D

Question 18

Which secondary structure is the strongest structurally? and which one has large angles within the amide bond?
A) A helix and A helix
B) A helix and B sheet
C) B strand and B sheet
D) B sheet and A helix

Answer 18

B

Question 19

Where does rotation about a bond in the aa backbone occur?
I. AlphaC-betaC II. N-AlphaC III. AlphaC-CarboxC IV. N-CarboxC
A) II, III
B) IV, II
C) I, II, III
D) All of the above

Answer 19

A

Question 20

Essentially, Alpha helices found in proteins are spiral in which ways?
A) Right handed
B) Left handed
C) Both, R & L, they flip after a Proline elbow
D) can be either, except for in Keratin

Answer 20

A

Question 21

What type of Reaction forms the Peptide bond in the primary structure of a protein and What is Released?
A) Hydration, CO2
B) Hydration,  O2
C) Reduction, O2
D) Dehydration, H20

Answer 21

D

Question 22

In an A helix, how many degrees are there between each A.A. residue?
A) 3.6
B) 3.5
C) 360
D) 100

Answer 22

D

Question 23

At greater than what percent is it said that you have a similiar protein when comparing proteins in the sliding analysis w/ use of Blos. 62?
A) 30%
B) 40%
C) 50%
D) 60%

Answer 23

B

Question 24

One for One pairing occurs between A.A. on ?
A) a helices 
B) B strands
C) B sheets parallel
D) B sheets anti parallel

Answer 24

D

Question 25

A   B   C  
hum A   V   G
cow  P   V   G
pigg S   V    E
Which column represents residue positions that are unable to tolerate substitutions?
A) 
B)
C)

Answer 25

B

Question 26

A   B   C  
hum A   V   N
cow  P   V   E
pigg L   V    D
goat Y   V    N
Which column represents residue positions that can tolerate conservative substitutions?
A) 
B)
C)

Answer 26

C
Must use blosum 62, and its +
think is structure similiar, E D are your two acids aspartic and glutamic, and then N is aspartine which is also similar.

Question 27

A   B   C  
hum A   V   G
cow  P   V   G
pigg  N   V    E
Which column represents residue positions that are highly variable?
A) 
B)
C)

Answer 27

A

Note Blosum 62, was -

Question 28

Blosum 62 reads conserved for which set of A.A.?
A)  H, L
B)  I, K
C) S, T
D) D, Y

Answer 28

C

Question 29

For collagen , what handedness are its individual Helices and its handedness of the 3 helices wrapped together?
A) Right, Left
B) Left, Right
C) Left, Left
D) Right, Right

Answer 29

B

Question 30

Collagen is Known for Its Repeated A.A sequence of ?
A) Pro- X - Ala
B) Glu - X - Gly
C) Gly - X - Ala
D) Gly - X - Pro

Answer 30

D