Test 1 Pretest Flashcards
0
Q
The hydrophobic Effect is known to be ? A) Exothermic B) Decreasing entropy C) Endergonic D) Exergonic
A
D Exergonic
1
Q
chemical reactions are driving by?
A)temperature B) Entropy C) Concentration D) Enzymes
A
C Concentrations
2
Q
Gibbs free energy (delta ) is \_\_\_\_\_\_\_\_\_\_ on the path? A) dependent B) independent C) interdependent D) sometimes dependent
A
B) independant
3
Q
Which level of Protein structure is the last level where only a single polypeptide chain is present and what are the bonds that provide this structure A) 2nd, Noncovalent interactions B) 2nd, Hydrogen Bonds C) 3rd, Hydrogen Bonds D) 3rd, Hydrophobic interactions
A
D) Hydrophobic interactions
4
Q
Which A.A. has one less Hydrogen in its Backbone? A) Tyrosine B) Proline C) Arginine D) Tryptophan
A
B) Proline
5
Q
At physiological pH, generally speaking, a basic and acidic A.A. will respectively have what charge? A) -, + B) +, - C) -, no charge D) +, no charge
A
B) +, -
6
Q
Is it true/false that All Branched Chain A.A. are Essential?
A
True L I V
PVT TIM HALL
7
Q
Which A.A. is most likely found in Cartilage? A) glycine B) alanine C) valine D) lysine
A
A) Glycine
8
Q
Near Physiological pH, due to charges, A.A.'s are also called? A) amphoteric B) amphipathic C) Ionic D) Zwitterions
A
D) Zwitterions
9
Q
The formation of Amide bonds are done so in what direction and is this Favorable or unfavorable? A) N to C Favorable B) N to C Unfavorable C) C to N Favorable D) C to N Unfavorable
A
B
10
Q
The approx pKa of The N and C terminus on an A.A. is ? A) 3 and 9 B) 2 and 8 C) 8 and 3 D) 10 and 2
A
C
11
Q
In columbs law, what does the D represent A) Diversion const. B) Density C) Displacement D) Dielectric const.
A
D
12
Q
Protein Structure is more Highly conserved than? A) A.A. Sequence B) Protein Subunit interaction C) Protein Hydrogen bonding D) Protein Hydrophobic interactions
A
A
13
Q
What are bovine ribonuclease and human ribonuclease, if they carry out a similar function? A) Homologs B) Orthologs C) Paralogs D) Interlogs
A
B
14
Q
The Keratin Heptad has how many residues per turn? A) 3.6 B) 3.5 C) 3.7 D) 1.8
A
B
15
Q
12 and 4 are the numbers of A.A. in what? Respectively A) Helix and Sheet B) Helix and Strand C) Sheet and Strand D) Sheet and Helix
A
B
16
Q
What two Fibrous Proteins provide structural support for the cells and tissues? A) Collagen and Keratin (alpha and Beta) B) Alpha Keratin and Beta Keratin C) Collagen and Alpha Keratin D) Collagen and Beta Keratin
A
C
17
Q
In Sheets and helices respectively, The H-bonds are in what orientation with the backbones? A) Parallel and Perpindicular B) Parallel and Parallel C) Perpendicular and Perpendicular D) Perpendicular and Parallel
A
D
18
Q
Which secondary structure is the strongest structurally? and which one has large angles within the amide bond? A) A helix and A helix B) A helix and B sheet C) B strand and B sheet D) B sheet and A helix
A
B
19
Q
Where does rotation about a bond in the aa backbone occur?
I. AlphaC-betaC II. N-AlphaC III. AlphaC-CarboxC IV. N-CarboxC
A) II, III
B) IV, II
C) I, II, III
D) All of the above
A
A
20
Q
Essentially, Alpha helices found in proteins are spiral in which ways?
A) Right handed
B) Left handed
C) Both, R & L, they flip after a Proline elbow
D) can be either, except for in Keratin
A
A
21
Q
What type of Reaction forms the Peptide bond in the primary structure of a protein and What is Released? A) Hydration, CO2 B) Hydration, O2 C) Reduction, O2 D) Dehydration, H20
A
D
22
Q
In an A helix, how many degrees are there between each A.A. residue? A) 3.6 B) 3.5 C) 360 D) 100
A
D
23
Q
At greater than what percent is it said that you have a similiar protein when comparing proteins in the sliding analysis w/ use of Blos. 62? A) 30% B) 40% C) 50% D) 60%
A
B
24
Q
One for One pairing occurs between A.A. on ? A) a helices B) B strands C) B sheets parallel D) B sheets anti parallel
A
D
25
Q
A B C hum A V G cow P V G pigg S V E Which column represents residue positions that are unable to tolerate substitutions? A) B) C)
A
B
26
Q
A B C hum A V N cow P V E pigg L V D goat Y V N Which column represents residue positions that can tolerate conservative substitutions? A) B) C)
A
C
Must use blosum 62, and its +
think is structure similiar, E D are your two acids aspartic and glutamic, and then N is aspartine which is also similar.
27
Q
A B C hum A V G cow P V G pigg N V E Which column represents residue positions that are highly variable? A) B) C)
A
A
Note Blosum 62, was -
28
Q
Blosum 62 reads conserved for which set of A.A.? A) H, L B) I, K C) S, T D) D, Y
A
C
29
Q
For collagen , what handedness are its individual Helices and its handedness of the 3 helices wrapped together? A) Right, Left B) Left, Right C) Left, Left D) Right, Right
A
B
30
Q
Collagen is Known for Its Repeated A.A sequence of ? A) Pro- X - Ala B) Glu - X - Gly C) Gly - X - Ala D) Gly - X - Pro
A
D
