Test 1 meds Flashcards
Amitriptyline
Tricyclic medications (TCAs) antidepressant
Tricyclic medications (TCAs)
Lines, pines, mines
“CAN’T SEE, CAN’T PEE, CAN’T EAT, CAN’T SHIT”
• Antidepressant (1st line)
• Increase appetite
• Given at night (drowsy); excreted in the urine
• Need a complete cardiac workup
• 10-14 days for effective
• 4-8 weeks therapeutic
Doxepin
Tricyclic medications (TCAs) antidepressant
Imipramine
Tricyclic medications (TCAs) antidepressant
Nortriptyline
Tricyclic medications (TCAs) antidepressant
Clomipramine
(only TCA used for OCD) antidepressant
Citalopram
Selective Serotonin Reuptake Inhibitor (SSRIs) Antidepressant 1st line
Escitalopram
Selective Serotonin Reuptake Inhibitor (SSRIs) Antidepressant 1st line
Fluoxetine
Selective Serotonin Reuptake Inhibitor (SSRIs) Antidepressant 1st line
Paroxetine
Selective Serotonin Reuptake Inhibitor (SSRIs) Antidepressant 1st line
Sertraline
Selective Serotonin Reuptake Inhibitor (SSRIs) Antidepressant 1st line
Selective Serotonin Reuptake Inhibitor (SSRIs)
Prams, tines
• Antidepressant (1st line)
• Great for anxiety
• Initial repose 1-3 weeks (21 days)
• Lower incidence of anticholinergic SE
• CAUTION WITH ELDERLY (falls, stroke, seizures)
• Black box warning for children, teens
• **Serotonin Syndrome (SES)- increase fever, increase BP, shock/death (when given with MAOI or too much SSRI)
• Fluoxetine d/c for 5 weeks before MAOI given; vise versa 2 weeks
Bupropion
Atypical Antidepressant (SNRIs) depression and smoking
Buspirone
Atypical Antidepressant (SNRIs) helps with anxiety and pain
Duloxetine
Atypical Antidepressant (SNRIs) good for severe depression and pain; can cause liver toxicity
Venlafaxine
Atypical Antidepressant (SNRIs) good for severe depression and GAD
Trazadone
Atypical Antidepressant (SNRIs) insomnia/antidepressant
Atypical Antidepressant (SNRIs)
Dual action, working form more than one issues • Antidepressant (1st line) • Anxiolytic • Takes 2-3 weeks • Sexual disfunction • Insomnia • No OTC or alcohol
Monoamine Oxidase Inhibitors (MAOI’s)
Tyramine diet!
No: Caffeine, cheese, Chinese, sour cream, avocado, yeast, sausage, pepperonis
• Antidepressant (2nd line)
• **Hypertensive crisis- increase b/p, c/p, stroke (occipital headaches), coma, death (interaction with food/drug)
• Monitor BP 2xdaily (notify MD in up)
No St. John’s wart acts as an antidepressant=counteractive
Phenelzine
Monoamine Oxidase Inhibitors (MAOI’s)
Isocarboxazid
Monoamine Oxidase Inhibitors (MAOI’s)
Tranylcypromine
Monoamine Oxidase Inhibitors (MAOI’s)
Selegiline transdermal system Patch (EMSAM)
Monoamine Oxidase Inhibitors (MAOI’s)
given to patients with Parkinson’s
Mood Stabilizer
Lithium
Mood stabilizer
- Therapeutic levels (0.4-1)
- 10-21 days to show improvement, Can take up to 3 weeks
- Increase fluids 1,500-3,000ml/day
- Renal and hypothyroidism eval.
- Labs 2x weekly, weekly, monthly
- Harmful to fetus
- No antidote=gastric lavage
Lithium
“normal” SE: fine hand tremors, polyuria, mild thirst/nausea, weight gain, discomfort
early warning signs of toxicity= slurred speech, muscle weakness
severe=2-2.5
give with food
Antiepileptic/anticonvulsant Drugs
- Controlling mania (2 weeks)
- Controlling depression (3 weeks)
- Helps with alcohol withdraw and benzos
- Choice drug for bipolar depression
- Liver toxicity (3.5-4.8 normal)
Carbamazepine
rapid cycling and severely paranoid and angry pts., blood/platelet count qweekly for 8 weeks “resistant mania”, 4-12,g bi weekly
Divalproex
monthly labs (LFT, PLT), acute mania not responding to lithium, 50-100 therapeutic, caution during pregnancy/childbearing years
Lamotrigine
bipolar depression, S/E SJS(rash), meningitis, long-term maintenance
Topiramate
depression in bipolar pts. With mania, aggressive behavior; what I took to help lose weight
Antipsychotics
Mood stabilizing properties
Olanzapine
Antipsychotics
1 of 2 FDA approved for maintenance treatment of Bipolar Spectrum disorder
Aripiprazole
Antipsychotics
1 of 2 FDA approved for maintenance treatment of Bipolar Spectrum disorder
Ziprasidone
Antipsychotics
Quetiapine
Antipsychotics
Risperidone
Antipsychotics