Test 1 - Antibacterial Treatments of Ocular Disease II

Question 1

What is FALSE about ocular diseases?

A) Most pathogenic cocci are gram (+) (straphylococcus, streptococcus)
B) Most pathogenic bacilli are gram (-) (pseudomonas and enteric)
C) bacterial culture results take 24-48 hours
D) Bacterial swab would be recommended for blepharitis and conjunctivitis

Answer 1

D) Bacterial swab would be recommended for blepharitis and conjunctivitis

Blepharitis and conjunctivitis are minor and do not justify the delay and expense of culture tests.

Question 2

Which cause would lab tests NOT be mandatory?

A) Neonatal opthalmia
B) Chronic Conjunctivitis
C) Corneal Ulcers
D) Orbital Cellulitis
E) Blepharitis
F) Endophthalmitis

Answer 2

E) Blepharitis

Question 3

Which drug IS NOT a bactericidal against gram (+) cocci?

A) Penecillin
B) Chloramphenicol
C) Cephalosporin
D) Fluoroquinolones
E) Bacitracin

Answer 3

B) Chloramphenicol

Question 4

Which drugs are bacteriostatic against gram (+) cocci? (Pick 3)

A) Tetracycline
B) Chloramphenicol
C) Cephalosporin
D) Erythromycin
E) Bacitracin

Answer 4

A) Tetracycline
B) Chloramphenicol
D) Erythromycin

Question 5

Which drugs are bacteriocidal against gram (-) bacilli? (Pick 3)

A) Ticarcillin
B) Chloramphenicol
C) Aminogylcosides
D) Fluoroquinolones
E) Tetracycline

Answer 5

A) Ticarcillin
C) Aminogylcosides
D) Fluoroquinolones

Question 6

Which drugs are bacteriostatic against gram (-) bacilli? (Pick 2)

A) Ticarcillin
B) Chloramphenicol
C) Aminogylcosides
D) Fluoroquinolones
E) Tetracycline

Answer 6

B) Chloramphenicol

E) Tetracycline

Question 7

Which drugs would be a good choice for topical treatment pending laboratory results? (Pick 2)

A) Penecillin
B) Gentamycin
C) Cephalosporin
D) Fluoroquinolones
E) Bacitracin

Answer 7

B) Gentamycin

E) Bacitracin

Question 8

What condition would NOT be treated with a topical route of administration?

A) Blepharitis
B) Conjunctivitis
C) Internal Hordeolum
D) External Hordeolum
E) Corneal Ulcer

Answer 8

C) Internal Hordeolum

Question 9

Which ocular infection would require oral administration for treatment? (Pick 3)

A) Internal Hordeoloum
B) External Hordeolum
C) Severe Conjunctivitis
D) Corneal Ulcers
E) Preseptal Cellulitis

Answer 9

A) Internal Hordeoloum
C) Severe Conjunctivitis
E) Preseptal Cellulitis

Question 10

Which ocular infection would require subconjunctival injections for treatment?

A) Internal Hordeoloum
B) External Hordeolum
C) Severe Conjunctivitis
D) Corneal Ulcers
E) Preseptal Cellulitis

Answer 10

D) Corneal Ulcers

Question 11

What is TRUE about AB and corneal penetration?

A) Many AB have good penetration of the cornea after topical administration
B) Inflammation decreases penetration of tissues in the eye
C) Ampicillin has good penetration into aqueous after topical administration
D) Cephalosporins penetrate the eye after systemic administration

Answer 11

D) Cephalosporins penetrate the eye after systemic administration (ampicillin as well)

• Many AB’s have poor penetration after topical administration
• Inflammation increases penetration of tissue in the eye
• Chloramphenicol has good penetration into aqueous after topical administration

Question 12

What is NOT a natural defense mechanism for fighting off bacterial infection?

A) Healthy Bacteria already in the eye
B) Tear film flushes bacteria and debris
C) Lysozymes, immunoglobulins and WBC
D) Intact Cornea
E) All are natural defenses

Answer 12

E) All are natural defenses