Test 1 Flashcards

1
Q

job is to envelop cell contents and give cell shape
semi permeable
made of phospholipid protein

A

cell membrane

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2
Q

control center

composed of DNA

A

nucleus

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3
Q

composed of RNA

rRNA synthesized processed

A

nucleoli

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4
Q

made of nucleic acids and protein

A

chromatin

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5
Q

chromatin that is dark staining, mature, inactive

A

heterochromatin

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6
Q

chromatin that is light staining, diffuse, immature, active

A

euchromatin

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7
Q

membrane that surrounds nucleus

A

nuclear envelope

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8
Q

system of stacked membranes

modifies and sorts and packages macromolecules for secretion

A

golgi body/complex

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9
Q

membrane lined tubules that go from nucleus to membrane

where proteins are stored and transported

A

ER

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10
Q

composed of rRNA and where proteins are synthesized

A

ribosomes

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11
Q

granules

membrane bound sacs that contain digestive enzymes

A

lysosomes

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12
Q

made of actin and myosin

provide support and assist in cell division

A

microfilaments

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13
Q

maintain cell shape

play a role in motility and mitosis

A

microtubules

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14
Q

play a role in mitosis
made of microtubules
only evident when cell is mitotic

A

centriole

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15
Q

hematopoiesis in the yolk sac

A

primitive hematopoiesis

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16
Q

hematopoiesis in the hepatic and medullary

A

definitive hematopoiesis

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17
Q

vein in bone marrow where mature cells will leave to go to peripheral blood

A

central sinus

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18
Q

areas in bone marrow that contain developing cells

A

hematopoietic cords

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19
Q

supply blood to bone marrow

A

central artery

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20
Q

network of supporting tissues for BM

made of macrophages, fibroblasts, adipocyes

A

stroma

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21
Q

cells that hold the cords together and regulate flow

A

endothelial cells

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22
Q

part of stroma, type of stem cells for other cells that aren’t blood cells

A

fibroblast

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23
Q

macrophage surrounded by developing RBCs

A

erythroblastic island

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24
Q

in spleen, old or damaged RBCs are removed by macs

A

culling

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25
in spleen, pluck out particles from RBC without destroying them
pitting
26
cells that can become any of specialized cells
pluripotent stem cell, hematopoietic stem cell
27
committed to a cell line
multipotent (unipotential)
28
precursors of a myeloid or lymphoid
progenitor cells
29
cells divide and multiply by mitotic divisions
proliferation
30
when cell differentiates from progenitor to mature
differentiation
31
cell death initiated by cell itself
apoptosis
32
glycoproteins that have a direct effect on hematopoiesis
growth factors, cytokines
33
production of WBCs
leukopoiesis
34
cells that contain granules in cytoplasm
granulocytes
35
not segmented and do not have granules
mononuclear cells
36
found very early in maturation non-specific, azurophilic contain myeloperoxidase, muramidase, defense's dark purple
primary granules
37
found in more mature cells may be red, red/orange, blue, pink contain lysozyme, collagenase, alkaline phosphatase, lactoferrin, plasminogen activators, heparin
secondary granules
38
found in neutrophils | pink/violet color
tertiary granules
39
part of cell death where nucleus becomes condensed, refractile
pyknosis
40
part of cell death where nuclei break up into fragments
karyorrhexis
41
part of cell death where nuclei are dissolved
karyolylsis
42
pool that contains stem and progenitor cells
mitotic pool
43
pool where maturation and proliferation occurs
storage pool
44
pool that consists of cells actually circulating in blood and can be counted
circulating pool
45
pool where WBC is attached to vessel walls
marginating pool
46
when neutrophil adheres to vein/vessel and penetrates through endothelia cell junctions into tissue
diapedesis
47
to prepare for dining, complement coats in or immunoglobulins
opsonization
48
when bacteria is inside of neutrophil within a vacuole
phagosome
49
total WBC count greater than 11,000
leukocytosis
50
increased WBC count not from a disease
pseudoleukocytosis
51
excessive leukocyte response to infection, inflammation, or neoplasm
leukemoid reaction
52
increase in WBC count with increase in immature RBCs
leukoerythroblastic reaction
53
decrease in WBC count less than 4000
leukopenia
54
neutrophil with greater than 5 lobes
hypersegmentation
55
bi lobed nucleus found by accident, autosomal dominant
pelger huet anomaly
56
underlying condition causing bi lobed nucleus
pseudo pelter huet anomaly
57
caused by bacterial infections, inflammation | granules become more numerous, larger, and darker staining
toxic granulation
58
single or multiple grey/blue inclusions near edge of cell made of rough ER
Dohle body
59
autosomal disorder of having dole like body inclusions in cytoplasm and also see giant platelets
may hegglin anomaly
60
large purplish granules, coarse, azurophilic, autosomal recessive skeletal abnormalities, facial abnormalities
alder reilly anomaly
61
rare autosomal recessive disorder characterized by giant lysosomal granules with abnormal membrane granule fusion, lethal
chediak higashi syndrome
62
antibodies against sheep RBCs
heterophile antibodies