Test 1 Flashcards

1
Q

Luminal amebacidals

A

Iodoquinol

Paramomycin

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2
Q

What is a SE of iodoquinol?

A

peripheral neuropathy and optic neuritis

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3
Q

systemic amebacidals?

A

Emetine and chloroquine

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4
Q

Mixed action Amebacidals?

A

Metronidazole and tinidazole (tinidazole is a 2nd gen more expensive drug )

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5
Q

What all is metronidazole used for?

A
DOC for amebas in combination with luminal agent 
also used for: 
> colitis
> giardia 
>Trichomonas vaginalis
>Anaerobic Gram neg. bacilli
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6
Q

What drug is an aminoglycoside antibiotic?

A

Paromomycin ( it is a luminal amebicide)

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7
Q

What is the MOA of metronidazole?

A

binds to DNA and proteins and kills the organism.

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8
Q

MOA of metronidazole?

A

orally. elimination is through the kidney

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9
Q

SEs of Metronidazole?

A

Nausea, GI disturbance, Metallic taste

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10
Q

Primaquine

A

eliminates exo-erythrocytic form of malaria

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