Test 1 Flashcards
1
Q
Luminal amebacidals
A
Iodoquinol
Paramomycin
2
Q
What is a SE of iodoquinol?
A
peripheral neuropathy and optic neuritis
3
Q
systemic amebacidals?
A
Emetine and chloroquine
4
Q
Mixed action Amebacidals?
A
Metronidazole and tinidazole (tinidazole is a 2nd gen more expensive drug )
5
Q
What all is metronidazole used for?
A
DOC for amebas in combination with luminal agent also used for: > colitis > giardia >Trichomonas vaginalis >Anaerobic Gram neg. bacilli
6
Q
What drug is an aminoglycoside antibiotic?
A
Paromomycin ( it is a luminal amebicide)
7
Q
What is the MOA of metronidazole?
A
binds to DNA and proteins and kills the organism.
8
Q
MOA of metronidazole?
A
orally. elimination is through the kidney
9
Q
SEs of Metronidazole?
A
Nausea, GI disturbance, Metallic taste
10
Q
Primaquine
A
eliminates exo-erythrocytic form of malaria