Test 1 Flashcards
4 Phases of Menstrual Cycle
Menstrual/Shedding
Proliferative/Follicular
Secretory Phase
Ischemic Phase
Menstrual Phase
- Functional 2/3 of endometrium is shed if NO pregnancy occurs
- Body retains basal layer of endometrium
Proliferative Phase/Follicular
- Rapid growth causing rebuilding of endometrial layer
Secretory phase
- Endometrium is thick velvet with rich blood supply and glandular secretions
- Supportive environment for fertilized ovum
- Layer regresses if NO fertilization
Ischemic Phase
- If no pregnancy, blood supply to endometrium is cut off and necrosis occurs
- Forces functional layer to separate from basal layer and menstrual bleeding occurs.
Ovulatory Phase
- 2 days before ovulation
- Final follicular maturation,
- Rise in LH and FSH, Progesterone, Decrease in Estrogen
Luteal Phase
- Progesterone is dominant hormone
- Begins after ovulation with release/rupture of ovum
- Corpus luteum secretes progesterone to support fertilized egg until placenta takes over, but regresses if implantation does not occur, as well as decline in progesterone/estrogen
Placenta Function
-Exchange nutrients/waste products between fetus and mom
-Forms at implantation and complete by week 12
-Produces hormones to maintain pregnancy
- Provides fetus with passive immunity in 3rd trimester
Placenta Structure
- formed from trophoblast
- Inner Membrane: Amnion
- Outer Membrane: Chorion
Amniotic Fluid
- 800-1200mL by end of pregnancy
- Surrounds, cushions, protects and allows for movement
- Maintains fetal body temp
- Allows for maturation of urinary, respiratory and GI tract (and auditory stimulation)
Umbilical Cord
- 2 arteries, 1 vein (AVA)
- Arteries carry deoxygenated blood/waste from fetus
-Vein carry deoxygenated blood/oxygen TO fetus
Subjective Signs of Ovulation
Abdominal Pain/Mittelschermz
Objective Signs of Ovulation
Body Temp - Increaes .5-1 degree day of
Pre/Post Mucus - Thick
Cervical Mucus - clear, egg white
Microscopic Ferning
Presumptive Signs of Pregnancy
MAY mean pregnancy
Amenorrhea
Breast Tenderness
Fatigue
Potential spotting
Probable Signs of Pregnancy
Indicative of pregnancy
- positive HCG
- Chadwick’s Sign - bluish cervix/vagina
- Hegar’s Sign - softening of uterine walls
- Goodell’s Sign - softening of cervix
Positive Signs of Pregnancy
Only result of fetus
Palpate mother pulse and find different sound using doppler
See fetus on US
Palpate fetal movement
Zygote
12-14 days post-ovulation
Ovum is fertilized until implanted in uterus
Embryo
3-8 weeks after fertilization
Embryo most vulnerable during first 8 weeks
Fetus
9 weeks after fertilization to 38+ weeks
Fewer anomalies caused by teratogens
Human Chorionic Gonadotropin
- HCG
- Peaks at 10 weeks, 50-70 days
- Glycoprotein
- Stimulates production of progesterone and estrogen in corpus luteum until placenta takes over
Estrogen
- Stimulates uterine development to create suitable environment
- Peaks at 32 weeks
Relaxin
- True pregnancy hormone
- Diminishes contraction strength and softens cervix
- Leads to long term collagen remodeling to allow ligaments to stretch
- Aids breast development
Prostaglandin
- Lipid
- Function unknown
- Thought to induce labor since it’s in high amounts at time of labor
Progesterone
- Maintains endometrium/decidua
- Relaxes smooth muscle to prevent spontaneous contractions
- Aids in breast development
- Peaks at 32 weeks