test 1 Flashcards
three functions of immunity
defense
homeostasis
surveillance
innate immunity
present at birth, first line defense against pathogens but not antigen specific
acquired immunity
developed immunity, 2 types: active and passive
natural active
from natural contact with pathogen, develops slowly, and is specific
natural passive
from mother to child. last months
artificial active
immunization with antigen. last years
artificial passive
injection of serum with antibodies, last several weeks
mostly composed of proteins, recognized as foreign and triggers immune system to produce antibodies
antigen
produced by lymphocytes in response to antigens, also called immunoglobulins
antibody
involved in differentiation and maturation of T lymphocytes
thymus gland
produce RBC, WBC, and platelets
bone marrow
humoral immunity
involved is B cells
produces antibodies and memory cells
fights against bacteria, extracellular viruses, resp and GI pathogens
cell mediated immunity
involved is T cells and macrophages
produces sensitized T cells and cytokines, and memory cells
fights against fungus, intracellular viruses, tumors
largest componet to Ig, found in plasma and interstital fluid. only Ig that can pass thru placenta
Protects bodily fluids
IgG
found in body secretion, lines mucous memb
protects bodily surfaces
IgA
Ig found in plasma, primary immune response
Protects blood stream
IgM
found in body secretion, lines mucous memb
protects body surfaces
IgA
Ig whose role isnt known
IgD
Ig responsible for allergic response. Mediated type 1 hypersensitivity
IgE
number 1 cause of death of elderly
bacterial pneumonia
decline of immune system from age
immunosenescence
RBC level
4-6
WBC level
5-10
PLT level
150-300
Hgb level
11-14
Hct level
30%
common BP med that has possible side effect of angioedema
ace inhibitor
whats included in CBC
RBC, WBC, PLT, Hgb, Hct
apheresis
autoimmunity treatment,
blood is taken and bad things are removed
high lactic acid in blood
something is wrong
primary immune disorder
missing a type of immune cell
secondary immune disorder
from meds, malnutrition, cancer, radiation, stress
most common immunosuppressive therapy
cyclosporine
hyperactive organ rejection
within 24 hours
acute organ rejection
within 6 months
chronic organ rejection
over months to years, manage symptoms
small proteins that help control growth and activity of other immune and blood cells
cytokines
localized infection that spreaded
disseminated
infection through out body
systemic
infection throughout body
systemic
different type of pathogens
bacteria
virus
fungi
protozoa
multicellular parasite
diseases that newly appeared or have existed but have been rapidly increasing
emerging infections
health care associated infections
health care acquired pneumonia (HAP)
Clostridium difficile (c-diff)
surgical site infections
catheter associated urinary tract infection (CAUTI)
central line associated bloodstream infection (CLABSI)
methicillin-resistant staphylococcus aureus (MRSA)
What’s needed for contact precautions
gloves, gown
what’s needed for droplet precautions
surgical mask
whats needed for airborne precautions
N-95
How is HIV transmitted
blood
semen
vaginal secretions
breast milk
normal range of CD4 T cells
800-1200
what is HIV
a retrovirus that destructs immune system damaging CD4 T cells
What range of CD4 T cells start having immune issues
> 500