Test 1 (12, 17, 28, 29, 31) Flashcards
Homeostasis
The state of equilibrium in the internal environment of the body.
Intracellular space
inside the cells; constitutes approx. 40% of body weight of an adult
extracellular space
outside the cells; consists of interstitial fluid, composed of the fluid in the interstitium (space between cells) and fluid contained within specialized cavities of the body (cerebrospinal fluid; fluid in the GI tract; and pleural, synovial, peritoneal, intraocular, and pericardial fluid.)
anion
ion that carries a negative charge (examples are bicarbonate (HCO3), chloride (CL) and phosphate (PO4)
cation
ion that carries a positive charge (examples are sodium (Na), potassium (K), calcium (Ca), and magnesium (Mg)
electrolyte
substance that dissociates in solution into ions (charged particles); a molecule of sodium chloride (NaCl) in a solution becomes Na+ and Cl-
monovalent
an ion that has the combining power of one hydrogen atom
nonelectrolyte
substance that dows not dissociate into ions in solution; examples include glocose and urea
osmolality
a measure of the total solute concentration per kilogram of solvent
osmolarity
a measure of the total solute concentration per liter of solution
solute
substance that is dissolved in a solvent
solution
homogeneous mixture of solutes dissolved in a solvent
solvent
substance that is capable of dissolving a solute (liquid or gas)
valence
the degree of combining power of an ion
diffusion
the movement of molecules from an area of high concentration to one of low concentration. it occurs in liquids, gases and solids.
facilitated diffusion
moves molecules from an area of high concentration to one of low concentration with assistance from a specific carrier molecule. Glucose transport into the cell is an example.
active transport
a process in which molecules move against the concentration gradient. external energy is required for this process. By active transport, sodium moves out of the cell and potassium moves into the cell to maintin this concentration difference, also refered to as the sodium-potassium pump. the energy source for this mechanism is adenosine triphosphate (ATP), which is produced in teh cell’s mitochondria.
osmosis
the movement of water between two compartments separated by a semipermeable membrane ( a membrane permeable to water but not to a solute).
osmotic pressure
the amount of pressure required to stop the osmotic flow of water
osmolality
measures the osmotic fouce of solute per unit of weight of solvent (mOsm/kg or mmol/kg)
osmolarity
measures the total milliosmoles of solute per unit of total volume of solution (mOsm/L)
plasma osmolality
measurement of the water balance of the body. Normal is 275 - 295 mOsm/kg
water deficit
a plasma value greater than 295 mOsm/kg indicates that the concentration of particles is too great or that the water content is too little. (hypertonic solution results in cellular shrinkage)
water excess
a plasma value less than 275 mOsm/kg indicates too little solute for the amout of wter or too much water for the amount of solute. (hypotonic solution results in cellular swelling)
isotonic
fluids with the same osmolality as the cell interior
hypotonic
solutions in whihc the solutes are less concentrated than the cells
hypertonic
those with solutes more concentrated than cells