Test 1 Flashcards

1
Q

Define

Physiology

A

study of the functions of an organism and its constituent parts

term physiology means the “study of nature” derived from the greek work physiologoi

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2
Q

What are the 3 strands of cellular physiology

A
  1. cytology - cell structure
  2. biochemical - chemistry of biological structure and function
  3. genetics - information flow
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3
Q

Who was Henrietta Lacks

A

1951 cervical tumour cells were removed from her

  • these cells grow very well in culture and do not age or die
  • names HeLa cells
  • used in research on viruses, cancers, and AIDS (cited in more than 70,000 research papers, plays and important role in the polio vaccine development)
  • Today: used for COVID vaccines, human genome, effects of toxins, drugs, hormones, radiation, poisons…)
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4
Q

What is cell theory

A
  • all organisms are made up of cells and their products
  • new cells arise only from preexisting ones
  • all cells have the same fundamental makeup
  • activities of an organism result from the co-operative working of groups of cells
  • cells depend on one another to survive
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5
Q

Characteristics of Living Matter

A
  • complicated and highly organized
  • each constituent has a specific function
  • extracts energy from the environment and synthesizes own complex structures from simple raw material
  • capable of precise reproduction
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6
Q

What is integration (in terms of human processes and systems)

A

process by which several components work together for a common, unified purpose (eg cardiac system works in tandem with the respiratory system)

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7
Q

What are the 6 Life processes?

A
  1. Metabolism
  2. Responsiveness
  3. Movement
  4. Growth
  5. Differentiation
  6. Reproduction
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8
Q

Life Processes

Metabolism

what is it? what is it composed of?

A

Is the sum of all chemical reactions in the body.
Composed of:
* Catabolism - the breakdown of complex chemical substances into simpler components.
* Anabolism - the formation of complex chemical substances from smaller, simpler components.

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9
Q

Life Processes

Responsiveness

A

Is the body’s ability to detect and respond to internal and external environmental changes.
* Cells of the body respond to environmental changes in characteristic ways

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10
Q

Life Processes

Movement

A

Is motion of the whole body, individual organs, single cells, and even tiny structures inside cells.
* Ex. Chewing food in your mouth, and grinding of food in your stomach.

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11
Q

Life Processes

Growth

A

Is an increase in body size that results from an increase in size of existing cells, an increase in the number of cells, or both.
* Could also include increased materials between cells
* Ex. Bone matrix
* Adipose cells (Size & Number)
* Muscle cells (size - hypertrophy, number of cells can increase until about 2 months old)

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12
Q

Life Processes

Differentiations

A

Is development of a cell from an unspecialized to a specialized state. Each type of cell in the body has a specialized structure and function that differs from that of its precursor cells.
* Ex. Red blood cells come from unspecified cell in bone marrow
* Precursor cells that undergo differentiation are known as stem cells.

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13
Q

Life Processes

Reproduction

A

Is either:
1. the formation of new cells for tissue growth,
repair, or replacement
2. the production of a new individual.

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14
Q

Why do we have feedback systems and feedforward control?

A

there are constant disturbances to the bodies homeostasis which must be regulated and controlled

feedback systems function to regulate

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15
Q

What is a negative feedback

A

Reverses a change in a controlled variable
How many variables in the body are controlled?

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16
Q

What is positive feedback?

A

strengthens or reinforces a change in a controlled variable
* blood clotting and platelets are a positive feedback loop
* stretch receptors in the cervix during childbirth

17
Q

what is feedforward?

A

Events which occur in anticipation of a change in a controlled variable
* mouth watering when before a tasty meal
* increase in heart rate before the start of a race

18
Q

Homeostatic imbalace (pathophysiology)

what does this lead to?

A

Can often lead to disease or death
* Disorder - Abnormality in function or structure
* Disease - Illness characterized by a recognizable set of signs and symptoms.
* Signs - objective changes that a clinician can observe and measure : fever or tired & thirsty (diabetes)
* Symptoms - subjective changes in body functions that are not apparent to an observer : headache

19
Q

Cellular Processes

(8)

A

■ Digestion
■ Energy Release and Consumption
■ Protein Synthesis
■ Lipid Synthesis
■ Packaging
■ Transport
■ Export
■ Cell Duplication

20
Q

What is the role of membranes?

A
  • compartmentalization: separates the cytoplasm (cytosol & organelles) from the ECF
  • Regulation of substance movement within and between cell
  • Detect arriving chemical messengers Link adjacent cells
  • Anchor cells to extracellular matrix
21
Q

Describe Membrane Structure

A

■ Mostly lipids & proteins
– Protein content is proportional to metabolic activity of the
membrane.
■ Lipid types within the membrane
– Phospholipids: creates rigidity
– Sphingolipids(orglyco): helps connect cells, importnat for signalling, establishing blood type
– Cholesterol: fights rigidity

22
Q

What is the role of cholesterol?

A

further reduces permeability to water
* compartmentalization
enhances membrane fluidity
* acts as a thermal buffer
* prevents chrystallization
* disrupts the hydrophobic interactions between phospholipids