TEST 1 Flashcards
Three phases of the ovarian menstrual cycle?
- follicular phase
2.ovulation
3.luteal phase
Hypothalamus secretes _____ that causes the pituitary gland to release _______.
GrNH, FSH
Adenomyosis
endometrial tissue exists within and grows into the uterine wall
4 stages of fetal development
1.zygotic
2.blastocyst
3.embryonic
4.fetal
Where does fertilization occur?
In the outer 3rd of the fallopian tube (5 hour long process that ends in pregnancy)
The ovum’s “thick outer layer” that the sperm penetrates to begin pregnancy
zona pellucida
Where do you want the fertilized egg to attach?
the upper portion of the posterior uterine wall
What is the volume of fluid at 10 weeks, 20 weeks and 37 weeks?
30ml @ 10 weeks
350ml @ 20 weeks
~1000 @ 37 weeks
How many chromosomes does each partner give?
the male and female both give 23 chromosomes
When is viability for a fetus?
20 weeks (only because lungs are developed at this point)
what happens at the 4th week of fetal development?
heart begins to beat
what happens at the 8th week of fetal development?
all body organs are formed
what happens at 12 weeks of fetal development?
sex of fetus can be determined and kidneys are able to secrete urine
what happens at 16 weeks of fetal development?
face looks like a human
what happens at 20 weeks of fetal development?
primitive respiratory movements begin, heartbeat can be heard on fetoscope and doppler and quickening occurs
what happens at 24 weeks of fetal development?
lecitin begins to appear in amniotic fluid and they can begin to hear
what happens at 28 weeks of fetal development?
brown fat (for thermoregulation), eyes can open and close and they have a weak suck reflex
what happens at 32 weeks of fetal development?
subcutaneous fat
what happens at 38 weeks of fetal development?
skin is pink, fetus receives antibodies from mom
how long and wide is the umbilical cord?
22inches long 1in wide
what is AVA in relation to the umbilical cord?
means the umbilical cord has two arteries and a vein
what are the 4 hormones the placenta produces?
progesterone, estrogen, HCG and hPL
How do you screen for syphillis?
with rapid plasma regain (RPR) an venereal disease research laboratory (VDRL)
What will a positive pregnancy test show to determine its positive?
High levels of HCG
What are the 4 phases of the endometrial (uterine) cycle?
- proliferation
2.secretory
3.ischemic
4.menstrual
What are the early signs of complications of oral contraceptives?
A bdominal pain may indicate liver/gallbladder issues
C hest pain or SOB may indicate pulmonary embolism
H eadaches may indicate increase BP or impending stroke
E ye problems may indicate increase BP or cerebral vascular incident
S evere leg pain may indicate a thromboembolic event
What are the early signs of complications of intrauterine devices?
P eriod late/pregnancy/abnormal periods
A bdominal pain/ pain with intercourse
I nfection exposure/abnormal vaginal discharge
N ot feeling well/fever/chills
S tring length (shorter/longer/missing)
What are presumptive signs of pregnancy?
(subjective)
-amenorrhea
-fatigue
-urinary frequency
-breast changes
-uterine enlargement
-quickening (movement)
What are probable signs of pregnancy?
(objective)
- positive urine pregnancy test
-hegors sign (softening of lower uterus)
-chadwicks sign ( bluish color of cervix)
-goodells sign (softening of cervix)
-ballottement (rebound of unengaged fetus)
-braxton hick contractions
-abdominal enlargement
Progesterone
“hormone of pregnancy”
-Produced by corpus luteum until about 12 weeks then produced by the placenta
-can be used to prolong pregnancy
Nagele’s Rule
LMP minus 3 months and add 7 days
LMP
last menstrual period
EDD
estimated date of delivery
EDC
estimated date of confinement
nulligravid
never pregnant
primigravid
one pregnancy
multigravid
more than one pregnancy
nulliparous
women who has not have a pregnancy beyond 20 weeks
primiparous
woman who has given birth once after a pregnancy of atleast 20 weeks
multiparous
woman who has had two or more births after a pregnancy of atleast 20 weeks
GTPAL
G- gravidity (# of pregnancies)
T-term pregnancies (>37 weeks)
P- preterm birth (24-37weeks)
A-abortions (spontaneous or induced)
L-living (how many living kids do you have)
Scheduled visits for an uncomplicated pregnancy
First visit 8 weeks
Second visit 12 weeks
Visits q 4 weeks until 28 weeks
Visits q 2 weeks until 36 weeks
Visits weekly until delivery
When should you give rhogam?
Rhogam at 28 weeks if mother is Rh negative and FOB is positive or unknown
Why is a RBC antibody screen used in early pregnancy, at 28 weeks and again at time of delivery during pregnancy?
to screen for antibodies in the blood of the mother that might cross the placenta and attack the baby’s red cells, causing hemolytic disease of the newborn (HDN).
If there are no Rh antibodies present at 28 weeks what happens?
the woman is given an injection of
Rh immune globulin (Rhogam) to clear
any Rh-positive fetal RBCs that may be
present in her bloodstream to prevent the production of Rh antibodies by the
mother.
What are the danger signs in pregnancy?
-sudden gush of fluid
-vaginal bleeding
-abdominal pain
-persistant vomiting
-epigastric pain
-edema of hands and feet
-severe persistent headache
-blurred vision/dizziness
-chills w/ fever over 100.4
-painful urination or decreased urine output
what is the indirect coombs test check ?
determines whether or not there are antibodies to the Rh factor in the mothers blood;
what is the purpose of an ultrasound?
useful to screen for ectopic pregnancies and anomalies
what does an ultrasound measure?
the clear (translucent) space in the tissue at the back of the baby’s neck; babies with abnormalities tend to accumulate more fluid back there
when is the screening ultrasound usually done and what does it examine?
18-20 weeks; heart, brain & spinal column. can determine sex
Describe a chorionic villus test (CVS)
-done under ultrasound guidance @ 12 weeks
-needle enters placenta to biopsy the cells
-diagnostic
-chromosomes are examined directly; can detect chromosomal abnormalities & test for certain genetic diseases
what 3 genetic diseases does a CVS test for?
sickle cell, tay-sachs, and hemophilia
describe amniocentesis
-done under ultrasound guidance @ 15-16 weeks
-needle enters placenta to remove fluid surrounding fetus
-diagnostic
-fluid can be sent to screen for neural tube defects such as spina bifida
amenorrhea vs dysmenorrhea
amenorrhea-absence of menses
dysmenorrhea- painful menses
what happens in endometriosis
tissue grows outside of the uterus
what are fibroids (leiomyomas)
noncancerous growths
what medications are used to treat polycystic ovary syndrome? (3)
-metformin
-spironolactone
-contraceptives
what should women who are Rh negative receive regarding an abortion?
Rhogam
describe progesterone only pills
works by thickening cervical mucus & making endometrium unfavorable for implantation
who should not take estrogen and progesterone pills
women over 35 yrs of age and smoke; or have a hx of DVT
when is the TDaP vaccine offered?
32 weeks
describe screening for gestational diabetes
@ 28 weeks ALL non diabetic pregnant women drink 50 gram glucose drink
what happens at each prenatal visit
-urine dip for protein&sugar
-weight
-BP
-listen for fetal heart tones after 12 weeks
-measure uterus(cm=weeks after about 20 weeks)
-at end of pregnancy, check fetal position and cervix for dilation and effacement
when do you do an early glucose screening?
for women with a BMI greater than 30
how is fundal height measured?
in centimeters from the pubic symphysis to the top most portion of the uterus
what are the functions of the amniotic fluid?
-maintains temperature for fetus
-allows for symmetric growth of fetus
-allows for buoyancy and movement of fetus
-acts as cushion to protect fetus and umbilical cord from injury
what labs are done at the first prenatal visit
-CBC w differential (look at MCV)
-platelets
-blood type and antibody screen
-hep b&c antibody virus
-rubella status
-syphilis status
-HIV
-urine
what are the 3 primary germ layers?
Ectoderm- outer layer
mesoderm- middle layer
endoderm-lining of tract
at what age can you see the forebrain and heart?
4 weeks
where is follicle stimulating hormone produced?
anterior pituitary gland
target organ of FSH?
ovaries
function of FSH?
responsible for maturation of the ovarian follicle- highest during follicular phase of reproductive cycle
What are the 3 types of estrogen?
estradiol- most common during child bearing age;
estriol- main estrogen during pregnancy;
estrone- the only estrogen produced after menopause
estrogen is secreted from what organ?
ovaries
target organ of estrogen?
ovaries; endometrial lining; multiple organs
function of estrogen?
Responsible for development of sex characteristics and reproductive development; promotes increased blood supply of endometrium resulting in a welcoming environment for the zygote, embryo and developing fetus; causes changes during pregnancy including nasal stuffiness, loosens pelvic ligaments and joints, hyperpigmentation and vascular changes in the skin; etc.; protects bone health; stabilizes cholesterol; protects heart, skin, brain, etc.
target organ of progesterone?
uterus
function of progesterone?
Levels increase just before ovulation. Reduces uterine contractions allowing the pregnancy to continue. (Called the hormone of pregnancy due to it’s calming effect).
hPL is secreted from where?
placenta
target organ of hPL?
maternal pancreas
function of hPL?
Acts as an antagonist against maternal insulin. Makes glucose available for fetal growth by altering maternal CHO, fat, and protein metabolism.
Prepares mammary glands for lactation.
hPL (human placental lactogen) is also known as?
hCS- human chorionic somatomammotropin
where is relaxin secreted from?
placenta and corpus luteum
target organ of relaxin?
uterus an ligaments of the pelvis
function of relaxin?
Works with progesterone to maintain pregnancy by suppressing release of oxytocin to delay onset of labor contractions; increase in flexibility of pelvis; works on dilation of cervix.
where is oxytocin secreted from?
posterior pituitary gland
target organ of oxytocin?
uterus and breasts
function of oxytocin?
Stimulates contraction of the uterus and milk ducts of the breasts.
where is prolactin secreted from?
anterior pituitary gland
target organ of prolactin?
breasts
function of prolactin?
promotes production of breast milk
what is hCG?
hormone that is measured for pregnancy testing; maintains maternal corpus luteum which secretes progesterone and estrogen
when do hCG levels peak?
60-70 days, then decrease until 100-130 days, then will remain at that lower level for the duration of pregnancy
What is zygotic stage?
fertilization of sperm and egg through 2nd week
What is blastocyst?
zygote divides into a solid ball of cells which attaches to the uterus
What is the embryonic stage?
major organs and structures begin to emerge by the end of 2nd week and through the 8th week
What is the fetal stage?
differentiation and structures specialize by end of 8th week until birth
What are the 3 germ layers?
ectoderm, mesoderm, endoderm (zygote in blastocyst stage transforms into there 3 layers)
responsibilities of ectoderm?
outer layer of skin, oil glands of hair follicles and skin, nails and hair, external sense organs, mucous membrane of mouth and anus
responsibilities of mesoderm?
true skin, skeleton, bone and cartilage, connective tissue, muscles, blood and blood vessels, kidneys and gonads
responsibilities of endoderm?
lining of trachea, pharynx, and bronchi; lining of digestive tract; lining of bladder and urethra
What is the the yolk sac?
a cavity that develops on the 9th day after fertilization which functions only during embryonic life
what does the yolk sac do?
initiates production of RBCs, continues until fetal liver takes over at about 6 weeks; the umbilical cord encompasses the yolk sac which then degenerates
What does the umbilical cord do?
fetal deoxygenated blood (CO2) and waste products leave the fetus through 2 umbilical arteries; oxygenated, nutrient rich blood from mother is transported to the fetus y 1 umbilical vein
What covers and cushions cord vessels?
wharton’s jelly
What is the placenta?
organ for fetal respiration, nutrition, and excretion