Terms Test 1 Flashcards
Positive Renforcement
he process by which presentation of a stimulus (drug) increases the probability of a response (non dependent drug taking paradigms)
Negative Reenforcement
A process by which removal of an aversive stimulus (negative emotional state of drug withdrawal) increases the probability of a response (dependence-induced drug taking)
Cannabinoids
Most commonly used illicit drug
Medicinal uses: antiemetic, appetite stimulant, anticonsulsant, and analgesic.
Abuse potential: More people sought treatment for marijuana than any other illicit drug.
Acute effects: slowed cognitive processing, impaired short-term memory, inhibition, concentration, visual-spatial processing. May precipitate psychotic disorder. Associated w/ relapse of other addicitons.
Long term effects: 9% become addicted. After one month of abstinence “minimal effects on cognition”, endocrine effects
Stimulants (cocaine, methamphetamines)
Increase monomaines (DA, NE, and 5HT)
DA- acutely enhance, but chronically depletes
Acute effects on CNS: energy, alertness, decreased appetite, anxiety, paranoia, irritability, siezures, increased HR, BP, and TMP.
Sedatives/Hypnotics
Most people become dependent when treating an anxiety disorder of insomnia.
Severe withdrawal (up to 50% of people on benzos)
Symptom rebound (anxiety, insomnia, muscle tension) lasts up to 3 weeks after discontinuation is mostly a withdrawal syndrome
Symptom reemergence is not a withdrawal syndrome. Reoccurence of original sx. Can last months.
Alcohol
Wide variety of target proteins unlke drugs that are more specific.
Adults metabolize avg. of 1 oz per 3 hours.
Withdrawal sx:
0-36 hrs: seuzures (BAC doesn’t have to equal 0 to start), increased HR, BP, Temp,
Alcohol + Tobacco = synergistic effects on risks for cancer
Abuse is common, but often undetected by medical staff.
Opiods
Risk w/ nonmedical or perscription abuse
OD can cause death (respiratory suppression)
Anhedonia makes dependence hard to break.
Abuse
An intense desire to obtain increasing amounts of a particular drug to the exclusion of all other activities
Dependence
The body’s physical need (addiction) to a specific drug. Dependence may result in physical harm, behavior problems, and association with people who also abuse drugs. Stopping can result in withdrawal.
Tolerance
A state of progressively decreased responsiveness to a substance.
Takes more to get high.
Compulsive Use
- Drug is taken in larger amounts or for longer periods.
- Persistent desire to or unsuccessful attempts at controlling use of substance
- Development of a substance centered lifestyle
- Neglect of signficant personal or social interests or obligations.
Leading COD’s Age 1-24
- ) Unintentional Injuries (38%)
- ) Homicide (13%)
- ) Suicide (12%)
- ) Cancer (7%)
- ) Heart disease (3%)
Leading COD’s Ages 25-44
- )Unintentional injuries (25%)
- ) Cancer (14%)
- ) Heart Disease (12%)
- ) Suicide (11%)
- ) Homicide (6%)
Leading COD’s Agest 45-64
- ) Cancer (32%)
- ) Heart disease (21%)
- ) Unintentional injuries (7%)
- ) Chronic lower respiratory disease (4%)
- ) Chronic liver disease and cirrhosis (4%)
Leading COD’s Ages 65+
- ) Heart Disease (27%)
- ) Cancer (22%)
- ) Chronic lower respirator disease (7%)
- ) Stroke (6%)
- ) Alzheimer’s disease (5%)
WHO ranking of national health care systems
Five factors:
- ) Health level (life expectancy; 25% weight)
- ) Responsiveness (Speed, privacy protections, choice of care; 12.5% weight)
- ) Financial Fairness (25% weight)
- ) Health Distribution (how equally resources are shared; 25% weight)
- ) Responsiveness distribution (how equally responsiveness if distributed; 12.5% weight)
U.S. ranked 37th.
ACA key points
- ) Expanded medicaid and increased number of plans subsidized
- ) Created/Encouraged ACOs to coordinate care delivery for specified populations (pay based on outcomes)
- ) ACOs will contract with PCMHs to deliever and coordinate care acoss the spectrum of patient needs.
IHI Triple Aim
- ) Experience of Care
- ) Population health
- ) Per capita cost
Normative
Counting or measuring a behavior, event, etc. then defining the most common as normal
Reliability
Consistency of prediction over time, over predictors, over individuals and/or over assesment techniques.
AKA repeatability