Terms (Calculation of Doses) Flashcards

1
Q

quantitative amount administered or taken by a patient for the intended medicinal effect

A

dose

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2
Q

the amount taken at one time

A

single dose

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3
Q

the amount taken during the course of therapy

A

daily dose/total dose

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4
Q

the schedule of dosing (ex. QID for 10 days)

A

dosage regimen

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5
Q

the amount that ordinarily produces the medicinal effect intended in the adult patient

A

usual adult dose

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6
Q

similarly defined for the infant or child patient

A

usual pediatric dose

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7
Q

the quantitative amounts of the drug that may be prescribed within the guidelines of usual medical practice

A

usual dosage range

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8
Q

the amount that produces the desired intensity of effect in 50% of the individuals tested

A

median effective dose

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9
Q

the amount that produces toxic effects in 50% of the individuals tested

A

median toxic dose

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10
Q

or priming dose, a larger than usual initial dose may be required to achieve the desired blood drug level

A

loading dose

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11
Q

the minimum concentration to produce the drug’s desired effects in a patient

A

median effective concentration (mec)

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12
Q

the concentration that produces dose-related toxic effects

A

minimum toxic concentration (mtc)

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13
Q

referred to as the primary drug treatment

A

monotherapy

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14
Q

additional to or supportive of a different primary treatment

A

adjunctive therapy

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15
Q

administered to protect the patient from contracting a specific disease (ex. vaccines)

A

prophylactic doses

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16
Q

contain pharmaceutical ingredients which provide the physical features, stability requirements, and aesthetic characteristics desired for optimal therapeutic effects

A

dosage forms

17
Q

examples of pharmaceutical ingredients

A

solvents, vehicles, preservatives, flavorants, fillers

18
Q

number of doses calculation

A

number of doses = total quantity/size of dose

19
Q

size of dose calculation

A

size of dose = total quantity/number of doses

20
Q

total quantity calculation

A

total quantity = number of doses x size of dose

21
Q

In using the equation, the total quantity and the size of dose must be

A

in the same unit of measure.

22
Q

the administration of doses that are much smaller than the usual dose of a drug

*Use of Aspirin in 81-mg amounts (rather than the usual dose of 325 mg) to lower the risk of heart attack and clot-related stroke.

A

low-dose therapy

23
Q

the administration of doses that are much larger than the usual dose of a drug

*Commonly associated with the chemotherapeutic treatment of cancer

A

high-dose therapy

24
Q

dosing options:

A

low-dose therapy and high-dose therapy

25
Q

products containing two or more therapeutic agents in fixed-dose combinations

A

fixed-dose combination products

26
Q

advantages of fixed-dose combination products

A

two or more needed drugs may be taken in a single dose which may be much more convenient, enhance compliance, and less expensive

27
Q

disadvantages of fixed-dose combination products

A

relative inflexibility in dosing

28
Q

*a number of tablets are scored, or grooved, to allow breaking into approximately equal pieces (usually halves)

*allows dosage flexibility, particularly when a patient is started at a half dose and then is titrated up to a full dosage level

*also enables a patient to take a product at a strength that is not otherwise available

A

table splitting and crushing

29
Q

It urges the use of a measuring device that either accompanies the product or is obtained separately and is calibrated to deliver the recommended dose

A

dose measurement

30
Q

calculations for number of doses, size of dose, and total quantity

A

general dose calculations