Terminology of Neoplasia Flashcards
1
Q
DNA Probe Analysis
A
- Used for detection of oncogenes; such as N-myc, bcr-c-abl gene products
2
Q
Flow Cytometry
A
- A measurement of DNA content of tumor cells (degree of ploidy)
3
Q
Carcinoembryonic Antigen (CEA)
A
- Onco-fetal antigen
- Expressed in carcinoma of colon, pancreas, lung, stomach and breast
4
Q
Carcinomas
A
- Malignant tumors arising from epithelial tissues
5
Q
Malignant tumor of glandular cells
A
- Adenocarcinoma
6
Q
Malignant tumor of squamous cells
A
- Squamous cell carcinoma
7
Q
Sarcoma
A
- Malignant tumors arising from connective tissue (i.e. bone, cartilage, fat, nerve) from mesenchymal cells outside the bone marrow
8
Q
Epithelial neoplasms terminology chart
A
9
Q
Mesodermal Connective tissue neoplasms chart
A
10
Q
Tumors which do not fit into orderly categories chart
A
11
Q
Cytokeratin
A
- Immunohistochemical brown-red reaction product stain in the neoplastic cells cytoplasm
*stain used for carcinomas and helps to distinguish carcinomas from sarcomas and lymphomas
*gastric adenocarcinoma is pos. for this stain
12
Q
Vimentin
A
- Immunohistochemical staining
*typical labeling reaction for sarcomas
13
Q
Tumor markers (Hormones)
A
- HCG- trophoblastic tumors and non-seminomatous testicular tumors
- Calcitonin- medullary carcinoma of thyroid
- Catecholamines and metabolites- pheochromocytoma and related tumors
- Ectopic hormones- paraneoplastic syndromes
14
Q
Onco-fetal tumor antigens
A
- Alpha-fetoprotein- liver cancer and non-seminomatous testicular tumors
- Carcinoembryonic antigen (CEA)- carcinoma of colon, pancrease, lung, stomach and breast
15
Q
Isoenzymes specific for cancers
A
- PSA- prostate cancer
- NSE- small cell carcinoma of lung, neuroblastoma
