Terminologies in introduction to pharmacology Flashcards

1
Q

What is Adverse Effect?

A

A possible dangerous pharmacological effect that is not intended and occurs when a medication is administered correctly.

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2
Q

What do you call the strength of binding between drug and receptor?

A

Affinity

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3
Q

What is antagonist in pharmacology?

A

It is a molecule that prevents the action of other molecules, often by competing for a cellular receptor; opposite of agonist.

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4
Q

What do you call the presence of a drug in the blood stream after it is administered?

A

Bioavailability

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5
Q

What is distribution in pharmacology?

A

It is the second stage of pharmacokinetics or the process by which medication is distributed throughout the body.

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6
Q

What is efficacy in pharmacology?

A

It is the maximum effect of which the drug is capable.

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7
Q

What do you call the final stage of pharmacokinetics or the process whereby drug byproducts and metabolites are eliminated from the body?

A

Excretion

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8
Q

What is First Pass Effect

A

It is the inactivation of the administered drugs in the liver and intestines.

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9
Q

What is the study of how drugs act at target sites of action in the body?

A

Pharmacodynamics

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10
Q

What is the study of how a person’s genetic make-up affects their response to medicines?

A

Pharmacogenetics

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11
Q

What is the study of how the body absorbs, distributes, metabolizes, and eliminates drugs?

A

Pharmacokinetics

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12
Q

What is therapeutic index?

A

It is a quantitative measurement of the relative safety of a drug that compares the amount of drug that produces a therapeutic effect versus the amount of drug that produces a toxic effect. Medication with a large therapeutic index is safer than a medication with a small therapeutic index.

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13
Q

What is agonist?

A

The opposite of antagonist, it is a drug capable of binding and activating a receptor, leading to a pharmacological response that may mimic that of a naturally occurring substance. Can be classified as full, partial or inverse

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14
Q

What is the process that alters the pH to less than 7?

A

Acidification

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15
Q

What is acromegaly?

A

It is a condition usually in middle-aged adults from hypersecretion of growth hormone

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16
Q

Afferent nerve

A

It transmits sensory information from peripheral organs to the brain and spinal cord (central nervous system).

17
Q

What do you call when it is pH less than 7.45 or a condition in which the tissues have relatively more acid or acid waste than normal; disturbance of acid-base balance; when the pH of the blood is below 7.35?

A

Acidosis

18
Q

What is Addison’s disease?

A

Inadequate secretion of glucocorticoids and mineralocorticoids.

19
Q

Adipose tissue

A

Tissue containing fat cells or fat.

20
Q

What is afterload in pharmacology?

A

It is a measure of the vascular resistance that the left ventricle must overcome in order to eject blood during contraction.