Terminologies in introduction to pharmacology Flashcards
What is Adverse Effect?
A possible dangerous pharmacological effect that is not intended and occurs when a medication is administered correctly.
What do you call the strength of binding between drug and receptor?
Affinity
What is antagonist in pharmacology?
It is a molecule that prevents the action of other molecules, often by competing for a cellular receptor; opposite of agonist.
What do you call the presence of a drug in the blood stream after it is administered?
Bioavailability
What is distribution in pharmacology?
It is the second stage of pharmacokinetics or the process by which medication is distributed throughout the body.
What is efficacy in pharmacology?
It is the maximum effect of which the drug is capable.
What do you call the final stage of pharmacokinetics or the process whereby drug byproducts and metabolites are eliminated from the body?
Excretion
What is First Pass Effect
It is the inactivation of the administered drugs in the liver and intestines.
What is the study of how drugs act at target sites of action in the body?
Pharmacodynamics
What is the study of how a person’s genetic make-up affects their response to medicines?
Pharmacogenetics
What is the study of how the body absorbs, distributes, metabolizes, and eliminates drugs?
Pharmacokinetics
What is therapeutic index?
It is a quantitative measurement of the relative safety of a drug that compares the amount of drug that produces a therapeutic effect versus the amount of drug that produces a toxic effect. Medication with a large therapeutic index is safer than a medication with a small therapeutic index.
What is agonist?
The opposite of antagonist, it is a drug capable of binding and activating a receptor, leading to a pharmacological response that may mimic that of a naturally occurring substance. Can be classified as full, partial or inverse
What is the process that alters the pH to less than 7?
Acidification
What is acromegaly?
It is a condition usually in middle-aged adults from hypersecretion of growth hormone