Terminologies in Introduction to Pharmacology Flashcards
Pharmacology
study of drugs and how they affect living beings, including their physical, chemical, biological, and physiologic impacts.
Clinical Pharmacology
human drug testing in healthy volunteers and patients
Pharmacotherapeutics
the application of medication to detect, prevent, or treat disease
Drug
any substance that can impact biological processes
Chemical Name
outlines the chemical composition of the medication
Generic Name
official, nonproprietary, not a trademark of any corporation, and widely used
Brand/Trade Name
proprietary name selected by the pharmaceutical firm and trademarked
Agonist
Drug that binds a receptor and produces a biochemical response
Antaginist
Binds the receptor but doesn’t produce a biochemical response “ it’s a blank” No second messenger is produced
Pharmacokinetics
investigation on how drugs pass through the body
Bioavailability
refers to the proportion of a medicine that has been supplied that is still active.
Distribution
body fluids transporting drug to places of action.
Biotransformation
via the activity of enzymes, convert medicines into a less active or inactive form.
Excretion
Pharmacodynamics
investigation on how medicines affect the body
Partial Agonist
insufficient affinities for receptor sites
Idiosyncratic Effect
rare drug response associated with hereditary predisposition
Paradoxical effect
the reverse of the desired medication effect
Toxicity
extent of negative effects brought on by high drug dosage
Prodrug
material that undergoes pharmacologic metabolism to become a substance