Termination Flashcards
How many terminations were there in 2012?
185,122 residents, 5,850 non-residents - mostly irish = 190,972
97% NHS funded
Highest rates are in southwark, lambeth and lewisham
When do terminations happen?
91% are before 13 weeks
77% are before 10 weeks
Only 160 were after 24 weeks
82 were selective terminations - 76% under ground E, 38 cases of twins to singleton
Terminations due to fetal abnormality
2,692 in 2012 –> 38% were chromosomal abnormalities
Methods of termination
52% were surgical – vacuum from 4-16weeks, dilation & evacuation 13 to 24 weeks
48% were medical – mifepristone and misoprostol (after 9 weeks may need multiple doses of misoprostol
Mifepristone
Competitive, reversible progesterone receptor blocker
this increases production and sensitivity of the uterus to prostaglandins - 200mg oral
Misoprostol
a £1 tablet which can be oral or pessary – 800ug
After 9 weeks consider giving additional doses 4hrly up to max of 4 times
Side effects of termination
Pain – NSAIDs but paracetamol no better than placebo
Also – nausea, vomiting, diarrhoea, faintness, hot flushes, headaches, breast pain, rash, facial oedema, hypotension, infections
Complications of medical terminations
Early – bleeding for up to 9 days
Retained products or infection – if pregnancy does not terminate there can be teratogenic effects
Late – retained placenta (6-10%), uterine rupture (<3%)
Methods of surgical termination
Cervical priming – given in all cases, misoprostol 400ug 3hrs prior to surgery. can also use osmotic dilators
Can use manual (up to 7 wks) or electric vacuum aspiration (up to 14wks) or D & E (14 to 24wks)
Risk factors for uterine or cervical damage during a surgical termination
under 17yrs old Advanced gestational age
cervical abnormalities Previous surgery
Inexperienced surgeon
Complications of early surgical termination
Ongoing pregnancy (examine aspirate for gestational sac and follow up HCG) - 0.5%
Uterine (0.5%) or cervical trauma (<1%)
Retained products or infection
Complications of late surgical termination
uterine perforation or cervical laceration uterine atony pelvic abscess Ashermann's syndrome DVT or PE
Antibiotic prophylaxis for terminations
Metronidazole PO/PR + Azthromycin 1g PO/doxycycline 100mg BD for 7 days
If negative for chlamydia just metronidazole
Fetocide
If gestation is over 21wks and 6 days it is recommended that the fetal heart is stopped before termination - intracardiac KCL injection
Long term complications of terminations
Possibly an increased risk of miscarraige or preterm delivery in future pregnancies
Possible increase in psychiatric illness