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flashcards ko > Teratogens > Flashcards

Teratogens Flashcards

To identify the agents and their effects on the unborn

1
Q

Neural tube defects
Orofacial clefts
Microcephaly
Nail or digit hypoplasia

A

Phenytoin

“Fetal Hydrantoin Syndrome”

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2
Q

Ebstein anomaly
Nephrogenic DI
Hypothyroidism

A

Lithium

Ebstein anomaly - atrialized right ventricle, malformed tricuspid valve

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3
Q

Neural tube defects (meningocele, myelomeningocele)

A

Valproate

decreases levels of folic acid increasing NTD

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4
Q

Microcephaly
Thymic hypoplasia
Small ears
Hydrocephalus

A

Isotrenitoin

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5
Q

Limb & craniofacial abnormalities
Neural tube defects
Abortion

A

Methotrexate

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6
Q

Renal dysgenesis

Oligohydramnios

A

ACE inhibitors

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7
Q

Nasal hypoplasia

Stippled epiphysis

A

Warfarin

“warfarin emybropathy” depression of nasal bridge and stippling (pinpoint calcification) of the epiphyses

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8
Q

What drug should be considered to be given instead to a patient treated for epilepsy or bipolar disorder when pregnacy is considered?

A

Levetiracetam

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9
Q

Short palpebral fissures
Smooth philtrum
Thin vermillion border

A

Alcohol

“Fetal Alcohol Syndrome”

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