Feb 2 block Flashcards

to retain the marked topics encountered

1
Q

CV: elevated creatine kinase post extraction of thrombus

A

reperfusion injury

– when cells within heart, brain or skeletal muscles are injured, enzyme creatine kinase leaks across damaged cell membrane and into circulation.

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2
Q

what events occur during reperfusion injury and in what situation does it happen

A

oxygen free radical generation, mitochondrial damage, inflammation

post thrombolytic therapy

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3
Q

how does furosemide become ototoxic?

A

inhibition of similar symporters (Na/K/Cl in the ascending loop of Henle) in the inner ear

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4
Q

what would be the predominant cell type found in bronchoalveolar lavage in a patient with Sarcoidosis?

A

lymphocytic predominance: high CD4/CD8 ratio.

because Sarcoidosis is a CD4 T cell mediateed disease.

CD 4 T cells release interferon gamma and TNF alpha to activate macrophage and granulation formation.

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