Teratogenic drugs Flashcards

1
Q

EtOH

A

FAH, microcephaly, CHD

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2
Q

Coumarin

A

Hypoplastic nasal bridge, chondrodysplasia punctata

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3
Q

Fluoxetine

A

Minor malformations, LBW, poor neonatal adaptation

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4
Q

Folic acid antagonists (like trimethoprim, phenytoin, carbamazepine, phenobarbital)

A

Neural tube defects, cardiovascular, renal and oral cleft defects

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5
Q

Isotretinoin and vitamin A

A

Facial and ear anomalies, congenital heart disease

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6
Q

Lithium

A

Epstein anomaly

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7
Q

Misoprostol

A

Arthrogryposis

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8
Q

Phenytoin

A

Hypoplastic nails, IUGR, typical facies

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9
Q

Radioactive iodine

A

Fetal hypothyroidism

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10
Q

Radiation

A

microcephaly

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11
Q

Streptomycin

A

deafness

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12
Q

Testosterone like meds

A

virilisation of femal

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13
Q

Tetracycline

A

enamel hypoplasia

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14
Q

Thalidamide

A

phocomelia

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15
Q

Solvent abuse (toluene)

A

Preterm labour, fetal alcohol like syndrom

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16
Q

Valproate

A

spina bifida

17
Q

Vitamin D

A

supraventricular aortic stenosis