Teratogenic drugs Flashcards
EtOH
FAH, microcephaly, CHD
Coumarin
Hypoplastic nasal bridge, chondrodysplasia punctata
Fluoxetine
Minor malformations, LBW, poor neonatal adaptation
Folic acid antagonists (like trimethoprim, phenytoin, carbamazepine, phenobarbital)
Neural tube defects, cardiovascular, renal and oral cleft defects
Isotretinoin and vitamin A
Facial and ear anomalies, congenital heart disease
Lithium
Epstein anomaly
Misoprostol
Arthrogryposis
Phenytoin
Hypoplastic nails, IUGR, typical facies
Radioactive iodine
Fetal hypothyroidism
Radiation
microcephaly
Streptomycin
deafness
Testosterone like meds
virilisation of femal
Tetracycline
enamel hypoplasia
Thalidamide
phocomelia
Solvent abuse (toluene)
Preterm labour, fetal alcohol like syndrom