Maternal drug SEs for neonates Flashcards

1
Q

Acetazolamide

A

Metabolic acidosis

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2
Q

Amiodarone

A

Bradycardia, hypothyroidism

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3
Q

Adrenal corticosteroids

A

Adrenal failure (rare)

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4
Q

Volatile anaesthetics

A

CNS depression

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5
Q

Aspirin

A

Bleeding, prolonged gestation

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6
Q

Blue cohosh herbal tea

A

Neonatal heart failure

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7
Q

Captopril/enalapril

A

Oligohydramnios, transient anuric renal failure

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8
Q

Cholinergic agents (pyridostigmine)

A

transient muscle weakness

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9
Q

CNS depressions in labour (narcotics, barbiturates, benzos)

A

CNS depression, hypotonia

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10
Q

Fluoxetine

A

Possible transient neonatal withdrawal, hypertonicity, minor anomalies

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11
Q

Haloperidol

A

withdrawal

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12
Q

Ibuprofen

A

Oligohydramnios, PPHN

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13
Q

Imipramine

A

withdrawal

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14
Q

Indomethacin

A

Oliguria, olidohydramnios, intenstional perforation, PPHN

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15
Q

Radioactive iodine

A

Goitre

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16
Q

Lead

A

reduced intellectual function

17
Q

Magnesium sulphate

A

Resp depression,. meconium plug, hypotonia

18
Q

Opiods

A

Withdrawal

19
Q

Nitrofurantoin

A

Hemolytic anaemia in G6PD def infants

20
Q

Oxytocin

A

Hyperbilirubinaemia, hyponatraemia

21
Q

Phenobarbitol

A

Vit K deficiency/bleeding, possible long term IQ reduction, sedation

22
Q

Primaquine

A

Hemolytic anaemia in G6PD def infants

23
Q

Propanolol

A

Hypoglycaemia, bradycardia, apnea

24
Q

Propylthiouracil

A

Goitre, hypothyroidism

25
Q

Sulfonamides

A

Interfere with protein bining of bilirubin, kernicterus at low levels of serum bilirubin, hemolysis with G6PD def

26
Q

Sulfonylurea

A

Refractory hypoglcyaemia

27
Q

Thiazides

A

Neonatal thrombocytopenia (rare)