Teratogenic Drugs Flashcards
Anticholinergics
Neonatal meconium ileus
ACE inhibitors
Renal failure
Decreased skull ossification
Renal tubular dysgenesis
Antithyroid drugs
Hypothyroidism and goitre
Carbamazepine
Neural tube defects
Cyclophosphamide
CNS malformations
secondary cancer
Danazol and other antiandrogens
Masculinization of female fetus
Diethylbesterol
Vaginal carcinoma and other genitourinary defects
Hypoglycemic drugs
Neonatal hypoglycemia
Lithium
Cardiovascular defects
Methotrexate
CNS and limb malformations
Misoprostol
Morphological abnormalities
NSAIDS
Constriction or closure of the ductus arteriosus
Phenytoin
Growth retardation
CNS defects
Psychoactive drugs (barbiturates, opioids, benzodiazepines)
Neonatal withdrawal syndrome
Systemic retinoids
CNS
Craniofacial
Cardiovascular