Teratogenesis Flashcards
ACE inhibitors
(-pril)
prolonged renal failure in neonates
decreased skull ossification,
renal tubular dysgenesis
Methotrexate
CNS and limb malformations
Anticholinergic drugs
> atropine
neonatal meconium ileus
Methimazole
aplasia cutis
rare malformation characterized by localized absence of the skin, mostly on the scalp
Carbamazepine
neural tube defects
Cyclophosphamide
CNS malformations and secondary cancer
Danazol
masculinization of female fetuses
NSAIDs
constriction of ductus arteriosus
necrotizing enterocolitis
Lithium
Ebstein anomaly
Rare heart problem where valve that separates the top and bottom right heart chambers does not form correctly
Warfarin
Skeletal and CNS defects,
Dandy- Walker syndrome
Dandy- Walker syndrome: cerebellum does not develop normally