Teratogenesis Flashcards

1
Q

ACE inhibitors
(-pril)

A

prolonged renal failure in neonates
decreased skull ossification,
renal tubular dysgenesis

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2
Q

Methotrexate

A

CNS and limb malformations

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3
Q

Anticholinergic drugs

> atropine

A

neonatal meconium ileus

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4
Q

Methimazole

A

aplasia cutis

rare malformation characterized by localized absence of the skin, mostly on the scalp

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5
Q

Carbamazepine

A

neural tube defects

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6
Q

Cyclophosphamide

A

CNS malformations and secondary cancer

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7
Q

Danazol

A

masculinization of female fetuses

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8
Q

NSAIDs

A

constriction of ductus arteriosus
necrotizing enterocolitis

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9
Q

Lithium

A

Ebstein anomaly

Rare heart problem where valve that separates the top and bottom right heart chambers does not form correctly

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10
Q

Warfarin

A

Skeletal and CNS defects,
Dandy- Walker syndrome

Dandy- Walker syndrome: cerebellum does not develop normally

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