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Dispensing 2 > Common Drug Toxicity > Flashcards

Common Drug Toxicity Flashcards

1
Q

Clozapine

A

Agranulocytosis

condition in which the absolute neutrophil count (ANC) is less than 100 neutrophils per microlitre of blood

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2
Q

Chloramphenicol
NSAIDs
Benzene

A

Aplastic Anemia

occurs when your bone marrow cannot make enough new blood cells for your body to work normally

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3
Q

Tricyclics
(-triptyline)
(-pramine)

Antidepressants

A

Atropine-like Side Effects

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4
Q

Doxorubicin
Daunorubicin

A

Cardiotoxicity

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5
Q

Fluoroquinolones
(Ciprofloxacin & Norfloxacin)

A

Cartilage Damage in children

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6
Q

Quinidine

A

Cinchonism

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7
Q

ACE Inhibitors
(-pril)

A

Cough

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8
Q

Lithium

A

Diabetes Insipidus

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9
Q

Metronidazole
Sulfonylureas (1st generation)

Sulfonylureas (1st generation)
> acetohexamide
> chlorpropamide
> tolazamide
> tolbutamide

A

Disulfiram-like effect

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10
Q

Antipsychotics

> Thioridazine
Haloperidol
Chlorpromazine

A

Extrapyramidal Side
Effects

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11
Q

Tetracycline
(-cycline)

A

Fanconi’s Syndrome

defect of proximal tubule leading to malabsorption

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12
Q

Valproic Acid
Halothane
Acetaminophen

A

Fatal Hepatotoxicity
(necrosis)

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13
Q

Phenytoin

A

Gingical Hyperplasia

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14
Q

Chloramphenicol

A

Gray Baby Syndrome

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15
Q

Cimetidine
Azoles
Spironolactone
Digitalis

A

Gynecomastia

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16
Q

Sulfonamides
Isoniazid
Aspirin
Ibuprofen
Primaquine

A

Hemolytic Anemia in
G6PD-deficiency

17
Q

Isoniazid

18
Q

Niacin
Tamoxifen
Ca++ Channel Blockers

Ca++ Channel Blockers
(-dipine)

A

Hot Flashes, Flushing

19
Q

Barbiturates
Phenytoin
Carbamazepine
Rifampin

A

Induce CP450

20
Q

Cimetidine
Ketoconazole

A

Inhibit CP450

21
Q

Methicillin
NSAIDs (except Aspirin)
Furosemide
Sulfonamides

A

Interstitial Nephritis

22
Q

Nitroglycerin

A

Monday Disease

loss of tolerance —-> headache, tach, dizziness upon re-exposure

23
Q

Rifampin

A

Orange Body Fluids

24
Q

Heparin
Corticosteroids

A

Osteoporosis

25
Q

Methyldopa

A

Positive Coombs’ Test

antibodies that act against your red blood cells

26
Q

Bleomycin
Amiodarone

A

Pulmonary Fibrosis

27
Q

Vancomycin

A

Red Man Syndrome

28
Q

MAOIs

> Isocarboxazid
Selegiline
Phenelzine

A

Severe HTN with
Tyramine

29
Q

Procainamide
Hydralazine

A

SLE-like Syndrome

autoimmune phenomenon where the patient develops symptoms similar to systemic lupus

30
Q

Antipsychotics

> Thioridazine
Haloperidol
Chlorpromazine

A

Tardive Dyskinesia

isorder that causes involuntary facial tics like lip-smacking and grimacing

31
Q

Aspirin
Quinidine

Dispensing 2 (2 decks)

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