Ten questions for the make up

Question 1

Define what is microtubule organizing center

Answer 1

It organizes an array of microtubules(control the location that radiate outward through the cytoplasm

Question 2

What is the major microtubule organizing center in animal cells?

Answer 2

The centrosome is the major microtubule organizing center in animal cells.

Question 3

Describe the location of integral membrane proteins N and C termini after reaching the plasma membrane

Answer 3

-depends on the topology of the protein
- If the protein is a single-pass transmembrane protein, the N-terminus are on the extracellular side and the C-terminues are on the cytoplasmic side

-If the protein is a multi-pass transmembrane protein, the N and C termini could be on either side of the membrane

Question 4

What happens to a protein that only has an N terminal ER signal peptide and does not get their mannose phosphorylated?

Answer 4

The protein will not be properly processed and may be remain in the ER or get degraded

Question 5

What happens to the N terminal ER signal peptide of a secreted protein?

Answer 5

The N terminal is cleaved off by signal peptides during protein translocation into the ER. The mature protein is then transported to the Golgi apparatus for further processing and secretion

Question 6

What happens to a protein that has an N terminal ER signal peptide and an ER retention sequence?

Answer 6

The protein will be translocated into the ER but will be retained in the Er.. The ER retention sequence prevents the protein from being transported to the Golgi apparatus and beyond