temperature Flashcards
what does homeothermic mean
maintain a relatively constant core body temperature in situations of fluctuating environmental temperature
where does the body get information from to remain homeothermic
the skin (information about external temperature)
CNS
viscera
where do the receptors transmit information to
hypothalamus + other areas of the brain
- there information is used to keep temperature constant
what does the body do when it needs to be cooled
thermogenesis (processes that generate/ release heat)
processes that minimise heat loss -> sweating, vasodilation and increasing basal metabolic rate
what does the body do when it needs to be warmed
involuntary responses -> shivering, piloerection, vasoconstriction
increase in the basal metabolic rate
what is pyrexia
fever
occurs to a resetting of the thermostat in the hypothalamus
a person with a fever will still regulate their body temperature to the external environment
what are the causes of pyrexia
infection
physical trauma
stress
what is the mechanism of the fever
1- the body releases endogenous pyrogens
- IL-4 and IL-6 (from macrophages)
2- these pyrogens act on the hypothalamus by inducing local prostaglandin production
3- resets the hypothalamic set points
- results in the body working to achieve a higher internal temperature (e.g. shivering)
what is the purpose of a fever
helps kill bacteria
higher rate of metabolism will produce a faster rate of healing
more rapid induction of defence mechanisms