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1-Scientific & lab basis of microbiology > Temp > Flashcards

Temp Flashcards

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Biology 101 flashcards
1
Q

Rickettsia species infecting humans in Canada

A

R. rickettsii

Possibly R. typhi and R. prowazekii

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2
Q

Rickettsia species that can cause fatal disease

A

R. rickettsii (4-23%)
R. prowazekii (13%)
R. conorii (21% of hospitalized)
R. typhi (4% of hospitalized)

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3
Q

Rickettsia species able to produce a latent infection (recrudescence years later)

A

R. prowazekii

“Brill-Zinsser disease”

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4
Q

Rickettsia spp. causing a CENTRIPETAL maculopapular rash with palm/plantar involvement (i.e. wrists and ankles to extremities to trunk)

A

R. rickettsii

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5
Q

Rickettsia spp. causing a CENTRIFUGAL maculopapular rash, with NO palm/plantar involvement (i.e. trunk to extremities)

A

R. prowazekii, R. typhi

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6
Q

Rickettsia spp. causing a maculopapular rash with an ESCHAR

A

R. conorii

R. parkeri (but sometimes vesicular)

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7
Q

Rickettsia spp. causing a VESICULAR rash with eschar

A

R. africae
R. akari
R. australis
R. parkeri (but sometimes maculopapular)

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8
Q

What general symptoms would make you think of Rickettsia spp.?

A 
FEVER
RASH (most; MP to vesicular)
HEADACHE
Myalgia
Arthralgia
Malaise
Abdo pain
Nausea
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9
Q

What shape are Borrelia spp.?

A

Spirochete (corkscrew)

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10
Q

What shape are Anaplasma spp.?

A

Pleomorphic

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11
Q

What shape are Ehrlichia spp.?

A

Pleomorphic

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12
Q

What shape are Orientia spp.?

A

Coccobacilli

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13
Q

What shape are Rickettsia spp.?

A

Coccobacilli

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14
Q

What’s missing from the cell wall of Borrelia spp.?

A

LPS

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15
Q

What’s missing from the cell wall of Anaplasma spp.?

A

LPS

PG

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16
Q

What’s missing from the cell wall of Ehrlichia spp.?

A

LPS

PG

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17
Q

What’s missing from the cell wall of Orientia spp.?

A

LPS

PG

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18
Q

What’s missing from the cell wall of Rickettsia spp.?

A

Nothing

Rickettsia have both LPS and PG

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19
Q

What cell types do Anaplasma multiply in?

A

PMNs

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20
Q

What cell types do Ehrlichia multiply in?

A

Monocytes

Except E.ewingii = PMNs

21
Q

What cell types do Orientia multiply in?

A

Monocytes

22
Q

What cell types do Rickettsia multiply in?

A

Vascular endothelial cells

23
Q

What is the vector that transmits Orientia spp.?

A

Chigger mite

24
Q

What is the vector that transmits Ehrlichia spp.?

A

Non-Ixodes ticks

25
Q

What is the vector that transmits Anaplasma spp.?

A

Ixodes ticks

26
Q

What is the vector that transmits Borrelia/Borreliella spp.?

A

Ticks (usually Ixodes, but not exclusively)

Exception: B.recurrentis = body lice.

27
Q

What is the approximate genome size of the obligate intracellular bacteria (e.g. Rickettsiales)?

A

1-2 Mb

28
Q

What are the member species of Borreliella burgdorferi sensu lato?

A

B. burgdorferi
B.afzelii
B.garinii
B.mayonii

(B. = Borreliella)

29
Q

What is the vector that transmits Borrelia recurrentis?

A

Human body louse

Pediculus humanis corporis

30
Q

What are the 2 species of Anaplasma that can cause human infections?

A

A. phagocytophilum

A. capra

31
Q

What are the 3 species of Ehrlichia that can cause human infections?

A

E. chaffeensis
E. ewingii
E. muris subsp. eauclairensis

32
Q

What are the species of Borrelia that can cause relapsing fever?

A

LOUSE-BORNE:
B.recurrentis

TICK-BORNE: 
B.hermsii
B.turicatae
B.parkeri
B.miyamotoi
...
33
Q

What are the 2 species of Orientia that can cause human infections?

A

O. tsutsugamushi

O. chuto

34
Q

What are the species of Borreli(ell)a that can cause Lyme disease?

A

B. burgdorferi sensu stricto
B.afzelii
B.garinii
B.mayonii

(B. = Borreliella)

35
Q

What are the species of Rickettsia that can cause murine typhus?

A

R. typhi

36
Q

What are the species of Rickettsia that can cause epidemic typhus?

A

R. prowazekii

Epidemic typhus, a.k.a. louse-borne typhus

37
Q

What are the species of Rickettsia that can cause louse-borne typhus?

A

R. prowazekii

Epidemic typhus, a.k.a. louse-borne typhus

38
Q

What are the species of Rickettsia that can cause spotted fever?

A 
R. africae
R. australis
R. conorii
R. japonica
R. parkeri
R. rickettsii
R. felis
...
39
Q

What vectors can transmit relapsing fever?

A

Ticks

Lice for B.recurrentis

40
Q

What vectors can transmit Lyme disease?

A

Ticks

41
Q

What vectors can transmit Human Granulocytotrophic Anaplasmosis?

A

Ticks

Attached for a few hours

42
Q

What vectors can transmit Human Monocytotropic Ehrlichiosis?

A

Ticks

Attached for >36h

43
Q

What vectors can transmit Scrub typhus?

A

Chigger mite

44
Q

What vectors can transmit Murine typhus?

A

Fleas

45
Q

What vectors can transmit Epidemic typhus?

A

Human body louse

46
Q

What vectors can transmit Rickettsial spotted fevers?

A

Ticks

R.felis = Fleas

47
Q

What vectors can transmit Rickettsial pox?

A

Mite

48
Q

What are the species of Rickettsia that can cause Rickettsial pox?

A

R. akari

1-Scientific & lab basis of microbiology (9 decks)

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