Linking diseases with the organisms that cause them

Question 1

What is invasive meningococcal disease?

Answer 1

Clinical evidence of invasive disease

+Lab confirmation of infection:

• Isolation of N.men from a normally sterile site (blood, CSF, synovial, pleural or pericardial fluid) OR
• N.men nucleic acid from a normally sterile site.

Probable Case

Clinical evidence of invasive disease with purpura fulminans or petechiae and no other apparent cause

+Non-confirmatory lab evidence:

• N.men antigen in the CSF OR
• N.men not isolated from a normally sterile site OR
• N.men nucleic acid not detected from a normally sterile site.

Question 2

What is invasive pneumococcal disease?

Answer 2

Clinical evidence of invasive disease{}

+Lab confirmation of infection:

• Isolation of S.pneumo from a normally sterile site (not including the middle ear) OR
• S.pneumo DNA from a normally sterile site (excluding the middle ear).

Question 3

What is the most common cause of LRTI in neonates?

Answer 3

Chlamydia trachomatis

Question 4

What is the most common cause of LRTI in infants?

Answer 4

RSV

Question 5

What is the most common cause of LRTI in 5-18mo’s?

Answer 5

S. pneumoniae

H. influenzae

Question 6

What is the most common cause of LRTI in young adults? (18-45yo)

Answer 6

M. pneumoniae

Question 7

What is the most common cause of LRTI in adults >45?

Answer 7

• S. pneumoniae*
• Legionella* spp.

Question 8

What is the most common cause of LRTI in institutionalized adults?

Answer 8

GNB’s

S. pneumoniae

S. aureus

Question 9

Food poisoning pathogens

Answer 9

S.aureus B.cereus C.perfringens

Question 10

What are risk factors for TB?

Answer 10

Living in an endemic area or in close contact with an infected individual Immunosuppresion, e.g.: Biologics HIV/AIDS Chemo/tpx Age

Question 11

What are the typical PSx of a pt with active TB disease?

Answer 11

Persistent cough (?=3 weeks) Sputum production (mb w blood) F, low grade Loss of appetite + weight loss Night sweats + chills SOB Chest pain

Question 12

List viruses that cause respiratory tract disease.

Answer 12

RSV Influenza viruses Parainfluenza viruses Human metapneumoviruses Adenoviruses Coronaviruses Rhinoviruses SARS-associated coronavirus

Question 13

List viruses that can be transmitted sexually.

Answer 13

HIV types 1 and 2 HSV HPV HBV HCV CMV

Question 14

List viruses that can cause systemic disease in immunocompromised patients.

Answer 14

HSV VZV CMV EBV Adenovirus

Question 15

List enteric viruses.

Answer 15

Norovirus Sapovirus Astrovirus Enteroviruses Rotaviruses Enteric adenoviruses

Question 16

List viruses that cause rash illnesses.

Answer 16

Measles Rubella Enteroviruses Parvovirus B-19 HHV6 HHV7

Question 17

List zoonotic viruses.

Answer 17

Hantavirus Rabies TBEV

Question 18

Diseases of Clostridioides difficile?

Answer 18

Pseudomembranous colitis, a severe life threatening infection of the colon

Question 19

What disease(s) can head lice carry?

Answer 19

None.

We just remove them because they’re itchy.

Question 20

What disease(s) can body lice carry?

Answer 20

1. Relapsing fever (Borreliella recurrentis)
2. Epidemic typhus (Rickettsia prowazekii)
3. Trench fever (Bartonella quintana)