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Medicine Year 3 > TCD 23 = Glomerulonephritis and Polycystic Kidney Disease > Flashcards

TCD 23 = Glomerulonephritis and Polycystic Kidney Disease Flashcards

1
Q

Glomerulonephritis

A
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2
Q

glomerulonephritis explanation

A

Is a condition where the filters in your kidneys are damaged and can often be caused by self immune system

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3
Q

Glomerulonephritis symptoms

A
  • Haematuria
  • Proteinuria
  • High blood pressure common with these patients
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4
Q

Nephrotic Vs Nephritic syndrome

A

Nephrotic
syndrome of proteinuria and hypoalbuminaemia
1. Low serum albumin
2. High urine protein content (>3+ protein on urine dipstick)
3. Oedema

Nephritic
syndrome of haematuria, some proteinuria, hypertension
1. Haematuria (either visible or detectable on urinalysis)
2. Oedema
3. Hypertension
4. Oliguria (<300mls/day)

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5
Q

Glomerulonephritis Causes/risks

A
  • Post infection
  • HIV
  • Lupus
  • Goodpastures
  • Vasculitis
  • Long term HTN
  • Diabetic nephropathy
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6
Q

Glomerulonephritis Diagnosis

A 
Urinalysis = blood, protein
FBC = CRP levels high, blood sugar high, creatinine levels 
CT = large kidney size 
USS = blockages
Biopsy = damage
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7
Q

Glomerulonephritis management

A

diet = eat less salt
Stop smoking
ACE inhibitors to lower blood pressure
Immunosuppressants - steroids

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8
Q

Polycystic Kidney Disease

A
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9
Q

Polycystic Kidney disease -explained

A

Is an inherited condition that causes small fluid-filled sacs called cysts to develop in the kidneys.
Doesn’t usually have a noticeable impact until 30+ years old

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10
Q

Polycystic Kidney Disease - symptoms

A
  • tummy (abdominal) pain
  • high blood pressure
  • haematuria (visible/non-visible)
  • potentially serious upper urinary tract infections (UTIs)
  • kidney stones
  • enlarged kidneys
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11
Q

Polycystic Kidney Disease - causes risk factors

A

mutation

family history of ADPKD

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12
Q

Polycystic Kidney Disease - Diagnosis

A 
diagnosis is usually in older age
urinalysis = blood, protein 
blood tests - creatinine 
EGFR test - would be low 
USS and CT - kidney damage
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13
Q

Polycystic Kidney Disease - Management

A

Treat HTN - ACE and ARBs
Don’t use NSAIDS - disrupt kidney function
Treat UTI
Treat Kidney stones
Treat kidney failure - dialysis, transplant
Avoiding damage to kidneys in sport

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14
Q

Vasculitis

A
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15
Q

Vasculitis - explained

A

inflammation of the blood vessels

- immune system attacks self blood vessels

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16
Q

Eosinophilic granulomatosis with polyangiitis EGPA - Churg Strauss

A

Asthma

Allergy symptoms

17
Q

Anti GBM / Goodpastures

A 
renal and pulmonary disease 
SOB
Haematuria 
Oedema 
Cough
18
Q

Granulomatosis and polyangitis - Wegners

A

blood vessels in nose, sinus, ears, lungs, kidneys

  • fever
  • night sweats
  • sinus inflammation
  • SOB
  • Kidney problems

Medicine Year 3 (2 decks)

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