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MCM > TBL7 > Flashcards

TBL7 Flashcards

Protein Modification and Signaling

1
Q

Pertussis Toxin

A

Inhibits Gi

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2
Q

Glycosylation

A

N-linked Asparagine
O-linked serine, threonine

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3
Q

Hydroxylation

A

add -OH group to proline
happens at every 3rd amino acid in collagen and stabilizes the triple helical structure

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4
Q

common antihistamines

Cetririzine

2nd generation, nonsedating

A

Zyrtec

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5
Q

common histamines

Levocetirizine

second, nonsedating

A

Xyzal

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6
Q

Fexofenadine

second generation nonsedating

A

Allegra

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7
Q

common histamines

Loratidine

second nonsedating

A

Claritin

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8
Q

Scurvy

A
  • collagen hydroxylation by prolyl-hydroxylase using Vit C as cofactor
  • hydroxylation every 3rd AA in collagen and stabilizes the triple helical structure
  • defective collagen
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9
Q

Signaling Pathway of Endocrine hormones

cAMP

A

FLAT ChAMPs CHuGG

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10
Q
A
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