ILS7 Flashcards

Histology of connective tissue and muscle

1
Q

appearance under microscope

Cardiac Muscle Tissue

A
  • striated
  • single nucleus, located centrally
  • arranged in branching network
  • intercalated discs and gap junctions
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2
Q

Human Muscle Disorders

A
  • genetic: muscular dystrophy
  • chronic pain: fibromyalgia
  • cancer (Sarcoma)
  • Coronary heart disease
  • infections (Lyme disease, malaria, and Rocky Mtn Fever)
  • physical injuries,
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3
Q

clinical conditions

human connective tissues

A

tendon tears, bony fractures, muscular compartment syndromes, cartilaginous injury, surgical disruption, direct inflammation

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4
Q

Autoimmune connective tissue diseases

A
  • SLE Systemic lupus erythematosus
  • Scleroderma (systemic sclerosis)
  • Rheumatoid Arthritis
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5
Q

Gene defect-related connective tissue disease

A
  • Ehlers-Danlos syndrome
  • Marfan syndrome
  • Scurvy
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6
Q

Scurvy

A
  • Vitamin C deficifiency needed to make collagen
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7
Q

Fibroblasts

A
  • play role in wound healing
  • synthesize connective tiss
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8
Q

Osteocytes

A
  • mature bone cells
  • hydroxyapatite crystals
  • control activity of osteoblasts and osteoclasts
  • increase bone mineralization
  • degeneration: increase bone respoption, decrease bone formation, loss of response to stress
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