TBL Syndromes

Question 1

Focal peripheral neurological syndromes

Answer 1

Acute
o Mechanical radiculopathy

Subacute
o Idiopathic facial neuropathy

Gradual
o Mechanical mononeuropathy
o Vestibular schwannoma

Episodic
o Trigeminal neuropathy

Question 2

Mixed central and peripheral neurological syndromes

Answer 2

Acute
o None

Subacute
o Thiamine deficiency neural syndrome
o Neuroborreliosis

Gradual 
o	B12 Deficiency neural syndrome
o	Alcoholic neural syndrome 
o	Human immunodeficiency virus neural syndromes 
o	Amyotrophic lateral sclerosis 

Episodic
o None

Question 3

Diffuse peripheral neurological syndromes

Answer 3

Acute
o None

Subacute
o Acute inflammatory demyelinating polyradiculoneuropathy

Gradual 
o	Diabetic polyneuropathy
o	Charcot-Marie-Tooth disease 
o	Autoimmune myositis 
o	Duchenne muscular dystrophy 

Episodic
o Myasthenia gravis

Question 4

Neurodevelopmental syndromes

Answer 4

• Chiari malformation
• Cerebral palsy
• Nerual tube defects

Question 5

Focal central neurological syndromes

Answer 5

Acute  
o	Ischemic stroke and transient ischemic attack
o	Non-traumatic intracerebral hemorrhage
o	Intracranial vascular malformation 
o	Mechanical myelopathy
o	Transient global amnesia

Subacute
o None

Gradual 
o	Pituitary adenoma 
o	Meningioma 
o	Nervous system metastases 
o	Astrocytoma 
o	Parkinson disease 

Episodic 
o	Focal seizures 
o	Dystonia 
o	Multiple sclerosis
o	Neurocysticercosis

Question 6

Diffuse Central Neurological Syndromes

Answer 6

Acute syndromes
o	Global cerebral hypoxia/hypoglycemia/ischemia 
o	Head trauma 
o	Osmotic neural syndromes
o	Aneurysmal subarachnoid hemorrhage 

Subacute
o Infectious meningitis
o Viral encephalitis

Gradual 
o	Hydrocephalus 
o	Essential tremor 
o	Giant cell arteritis 
o	Huntington disease 

Episodic 
o	Primary headaches
o	Generalized tonic-clonic seizures
o	Febrile seizures 
o	Absence seizures