TBL Hormone Unknown

Question 1

A Dx of DM is made if the subject has: A “casual” plasma glucose conc. of

Answer 1

≥ 200 mg/dl, plus symptoms of diabetes, e.g., polyuria, polydipsia, weight loss (i.e., the classic symptoms). [“Casual” means any time of day without regard to the time of the last meal.]

Question 2

A Dx of DM is made if the subject has: Fasting plasma glucose [FPG] conc. of

Answer 2

≥ 126 mg/dl (7.0 mM). [“Fasting” means no caloric intake for ≥ 8 hours.]

Question 3

A Dx of DM is made if the subject has: A 2-hr plasma glucose [PG] conc. of

Answer 3

≥ 200 mg/dl (11.1 mM) in a standard oral glucose tolerance test [OGTT], using a dose of 75 grams of glucose.

Question 4

A Dx of DM is made if the subject has: Hb A1c : ≥

Answer 4

Hb A1c : ≥ 6.5% (blood taken anytime; fasting not required; acute illness & stress have only small effects)

Question 5

The OGTT is not recommended for routine clinical use. Unless?

Answer 5

he subject has unequivocal hyperglycemia with acute metabolic decompensation, these criteria should be confirmed by repeat testing on a different day.

Question 6

What is “normal” ? FPG is:

Answer 6

FPG is: < 100 mg/dl: “Normal Fasting Glucose”,

Question 7

What is “normal” ? The 2 hr value in an OGTT is:

Answer 7

The 2 hr value in an OGTT is: < 140 mg/dl: “Normal Glucose Tolerance”.

Question 8

What is “normal” ? Hb A1c :

Answer 8

Hb A1c : < 5.7%

Question 9

But what about intermediate values ? “Pre-diabetes”

From the fasting plasma glucose conc.:

Answer 9

If FPG is: ≥ 100 and < 126 mg/dl, the Dx is “Impaired Fasting Glucose” (IFG).

Question 10

But what about intermediate values ? “Pre-diabetes”

From an OGTT:

Answer 10

If the 2 hr PG is ≥ 140 and < 200 mg/dl, the Dx is “Impaired Glucose Tolerance” (IGT).

Question 11

But what about intermediate values ? “Pre-diabetes”

Hb A1c

Answer 11

Hb A1c : 5.7% - 6.4%

Question 12

“Pre-diabetes” subjects have an increased risk?

Answer 12

For diabetes

Question 13

Gestational diabetes – the criteria and OGTT testing are?

Answer 13

Slightly different.

Question 14

Gestational diabete “Screening test” at?

Answer 14

24-28 weeks, if +, then a “diagnostic test” is performed. However, certain patients are considered so “at risk” that the screening test is skipped, going straight to the “Dx test”.

Question 15

Gestational diabete Other subjects are considered to have such a slight risk that they?

Answer 15

Do not need screening. But to be in this class, they must have all of the following: <25 y, normal wt., no first degree relative with DM, and not Hispanic, African-American, Asian, native American, or Pacific Islander, and no family history of diabetes.