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Endocrine System > HYPOTHALAMIC and ANTERIOR PITUITARY DISORDERS > Flashcards

HYPOTHALAMIC and ANTERIOR PITUITARY DISORDERS Flashcards

1
Q

Hormones inhibited by somatostatin

A 
Acetylcholine
Arginine vasopressin
Cholecystokinin
Epidermal growth hormone
Glucagon
Gastrin
Gastric inhibitory polypeptide
Growth hormone
Insulin
Motilin
Neurotensin
Pancreatic polypeptide
Secretin
Serotonin
Substance P
Thyrotropin
Vasoactive intestinal polypeptide
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2
Q

RESULTS of PITUITARY HORMONE DEFICIENCIES

HORMONE: GH CLINICAL SYNDROME

A

children: short stature
adults: various effects

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3
Q

RESULTS of PITUITARY HORMONE DEFICIENCIES

HORMONE: FSH CLINICAL SYNDROME

A

infertility

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4
Q

RESULTS of PITUITARY HORMONE DEFICIENCIES

HORMONE: LH CLINICAL SYNDROME

A

men: hypogonadism, reduced sperm count
women: hypogonadism, amenorrhea, oligomenorrhea

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5
Q

RESULTS of PITUITARY HORMONE DEFICIENCIES

HORMONE: TSH CLINICAL SYNDROME

A

hypothyroidism

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6
Q

RESULTS of PITUITARY HORMONE DEFICIENCIES

HORMONE: ACTH CLINICAL SYNDROME

A

hypoadrenalism, loss of pigmentation

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7
Q

RESULTS of PITUITARY HORMONE DEFICIENCIES

HORMONE: Prolactin CLINICAL SYNDROME

A

Sheehan’s syndrome

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8
Q

RESULTS of PITUITARY HORMONE DEFICIENCIES

HORMONE: ADH CLINICAL SYNDROME

A

diabetes insipidus

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9
Q

RESULTS of PITUITARY HORMONE DEFICIENCIES

HORMONE: Oxytocin CLINICAL SYNDROME

A

? failure of milk letdown

? post-partum uterine bleeding,

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10
Q

ONLY HUMAN GROWTH HORMONE?

A

IS EFFECTIVE!

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11
Q

SECRETORY PITUITARY TUMORS HORMONE EXCESS EFFECT PROLACTIN (FEMALES)

A 
AMENORRHEA
OLIGOMENORRHEA
GALACTORRHEA
INFERTILITY
OSTEOPENIA
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12
Q

SECRETORY PITUITARY TUMORS HORMONE EXCESS EFFECT PROLACTIN (MALES)

A

HYPOGONADISM
DECREASED LIBIDO
GALACTORRHEA (RARE)
PITUITARY DEFICIENCIES

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13
Q

SECRETORY PITUITARY TUMORS HORMONE EXCESS EFFECT ACTH

A

CUSHING’S DISEASE

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14
Q

SECRETORY PITUITARY TUMORS HORMONE EXCESS EFFECT GROWTH HORMONE

A

ACROMEGALY

GIGANTISM

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15
Q

SECRETORY PITUITARY TUMORS HORMONE EXCESS EFFECT GONADOTROPINS

A

(RARE)
VISUAL DISTURBANCE
HEADACHES
HYPOGONADISM

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16
Q

SECRETORY PITUITARY TUMORS HORMONE EXCESS EFFECT TSH

A

(RARE)

HYPERTHYROIDISM

17
Q

ETIOLOGY of ACROMEGALY

A

Excess growth hormone secretion: Pituitary (98%) GH - cell adenoma (60%), [Mixed GH-cell, & Prolactin-cell adenoma (25%)], & Mammosomatotroph-cell adenoma (10%)
Excess growth hormone-releasing hormone secretion
Excess growth factor activity

18
Q

Risks of Long-term Exposure to Elevated Serum Growth Hormone (GH) Concentrations

A 
Arthropathy
Hypertension
Neuropathy
Respiratory disease
Cardiovascular disease: Cardiomyopathy
Malignancy
Carbohydrate intolerance: Diabetes mellitus

Endocrine System (6 decks)

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