TBL #2 Prep Flashcards

1
Q

What are some weird things that can stimulate the release of GH?

A
starvation
hypoglycemia
decreased fatty acids
exercise
stress trauma
sleep
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2
Q

What is something strange that can stimulate the release of TSH?

A

hypothermic conditions

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3
Q

What are some things that can increase the release of prolactin?

A

sleep
stress
dopamine antagonists

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4
Q

What does CRH do to appetite?

A

It suppresses it.

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5
Q

What processes does FSH regulate?

A

ovarian folliculogenesis
estrogen synthesis
spermatogenesis in sertoli cells

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6
Q

What processes does LH regulate?

A

ovulation
formation of a corpus luteum
estrogen, progesterone, testosterone synthesis

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7
Q

What are the effects of GH?

A

production of IGF
decreased glucose uptake into cells
increased lipolysis
increased protein synthesis

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8
Q

Aside from lactogenesis & breast development, what else does prolactin stimulate?

A

it inhibits ovulation

blocks GnRH

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9
Q

T/F ACTH controls aldosterone.

A

TRUE

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10
Q

What is a cause of secondary over-secretion of CRH?

A

stressful events

infection

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11
Q

What is a cause of secondary over-secretion of prolactin?

A

destruction of the hypothalamus–>loss of dopamine

no inhibitor–over-secretion!

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12
Q

What is Hashimoto’s Disease?

A

primary hypothyroidism
Elevated TSH
Low T3, T4
autoimmune attack of: TSH receptors, TPO, thyroglobulin & thyroid follicles

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13
Q

What are the symptoms of Hashimoto’s Disease?

A

weight gain, depression, temperature sensitivity, chronic fatigue, muscle weakness

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14
Q

What happens when you have a prolactinoma?

A

you secrete too much prolactin into the blood.
missed periods
men secreting milk out of their breasts
decreased libido

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15
Q

What are the symptoms of Cushing’s Disease?

A
tumor on the pituitary gland--increases levels of ACTH & therefore Cortisol.
Weight Gain
HTN
Amenorrhea
Osteoporosis
Skin Changes
Immune Suppression
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16
Q

What does it mean when you are talking about the hypothalamus & pituitary gland & talking about 1, 2, & 3 over-secretions of hormones?

A

1ary: @ the level of the target organ
2ndry: @ the level of the pituitary gland
3ry: @ the level of the hypothalamus

17
Q

Which 3 hormones does the adrenal gland release?

A

aldosterone
DHEA
Cortisol

18
Q

Where is each hormone of the adrenal gland synthesized & released?

A

Aldosterone: Zona Glomerulosa (outer layer of the adrenal cortex)
Cortisol: Zona Fasciculata (middle layer of the adrenal cortex)
DHEA: Zona Reticularis (inner layer of the adrenal cortex)

19
Q

Which of the hormones released from the adrenal cortex is stimulated by ACTH?

A

DHEA

cortisol

20
Q

What are the effects of cortisol?

A

goes to the liver–>gluconeogenesis–>raises blood glucose

downregulated B cell mediated immunity

21
Q

What does DHEA do?

A

goes to the testes

a precursor to testosterone

22
Q

What are the symptoms of hyperaldosteronemia?

A

low volumes of conc’n urine
HTN
alkalosis
hypokalemia

23
Q

How can you distinguish primary over-secretion from secondary over-secretion?

A

Primary Over-Secretion: Low ACTH, High Cortisol

Secondary Over-Secretion: High ACTH, High Cortisol

24
Q

Where does the T3 & T4 work in the body?

A

everywhere except the spleen & testes

25
Q

What does thyroid hormone do to the BP?

A

it increases pulse pressure; raises systolic & lowers diastolic

26
Q

What are the symptoms of hyperthyroidism?

A
excitable
intolerant to heat
increased sweating
weight loss
increased frequency of bowel movements
muscle weakness
hand tremors
27
Q

What are the symptoms of hypothyroidism?

A

fatigue, muscle weakness, slow heart rate, weight gain, constipation, goiters

28
Q

What is the effect of parathyroid hormone in the kidney?

A

stimulates reabsorption of calcium

inhibits reabsorption of phosphate

29
Q

What is the effect of parathyroid hormone on the intestines?

A

causes more absorption of calcium & phosphate via Vitamin D