TBL #2 Prep Flashcards
What are some weird things that can stimulate the release of GH?
starvation hypoglycemia decreased fatty acids exercise stress trauma sleep
What is something strange that can stimulate the release of TSH?
hypothermic conditions
What are some things that can increase the release of prolactin?
sleep
stress
dopamine antagonists
What does CRH do to appetite?
It suppresses it.
What processes does FSH regulate?
ovarian folliculogenesis
estrogen synthesis
spermatogenesis in sertoli cells
What processes does LH regulate?
ovulation
formation of a corpus luteum
estrogen, progesterone, testosterone synthesis
What are the effects of GH?
production of IGF
decreased glucose uptake into cells
increased lipolysis
increased protein synthesis
Aside from lactogenesis & breast development, what else does prolactin stimulate?
it inhibits ovulation
blocks GnRH
T/F ACTH controls aldosterone.
TRUE
What is a cause of secondary over-secretion of CRH?
stressful events
infection
What is a cause of secondary over-secretion of prolactin?
destruction of the hypothalamus–>loss of dopamine
no inhibitor–over-secretion!
What is Hashimoto’s Disease?
primary hypothyroidism
Elevated TSH
Low T3, T4
autoimmune attack of: TSH receptors, TPO, thyroglobulin & thyroid follicles
What are the symptoms of Hashimoto’s Disease?
weight gain, depression, temperature sensitivity, chronic fatigue, muscle weakness
What happens when you have a prolactinoma?
you secrete too much prolactin into the blood.
missed periods
men secreting milk out of their breasts
decreased libido
What are the symptoms of Cushing’s Disease?
tumor on the pituitary gland--increases levels of ACTH & therefore Cortisol. Weight Gain HTN Amenorrhea Osteoporosis Skin Changes Immune Suppression
What does it mean when you are talking about the hypothalamus & pituitary gland & talking about 1, 2, & 3 over-secretions of hormones?
1ary: @ the level of the target organ
2ndry: @ the level of the pituitary gland
3ry: @ the level of the hypothalamus
Which 3 hormones does the adrenal gland release?
aldosterone
DHEA
Cortisol
Where is each hormone of the adrenal gland synthesized & released?
Aldosterone: Zona Glomerulosa (outer layer of the adrenal cortex)
Cortisol: Zona Fasciculata (middle layer of the adrenal cortex)
DHEA: Zona Reticularis (inner layer of the adrenal cortex)
Which of the hormones released from the adrenal cortex is stimulated by ACTH?
DHEA
cortisol
What are the effects of cortisol?
goes to the liver–>gluconeogenesis–>raises blood glucose
downregulated B cell mediated immunity
What does DHEA do?
goes to the testes
a precursor to testosterone
What are the symptoms of hyperaldosteronemia?
low volumes of conc’n urine
HTN
alkalosis
hypokalemia
How can you distinguish primary over-secretion from secondary over-secretion?
Primary Over-Secretion: Low ACTH, High Cortisol
Secondary Over-Secretion: High ACTH, High Cortisol
Where does the T3 & T4 work in the body?
everywhere except the spleen & testes
