TB PREVENTION/PROPHYLAXIS Flashcards
What is the recommended duration of isoniazid monotherapy for tuberculosis preventive treatment?
A) 1 month
B) 3 months
C) 4 months
D) 6 or 9 months
Answer:
D) 6 or 9 months
Rationale:
Isoniazid monotherapy for tuberculosis preventive treatment is recommended for 6 or 9 months. This regimen is effective but requires long-term adherence, which can be challenging for some patients.
Which tuberculosis preventive regimen is recommended for both adults and children under 10 years old?
A) Isoniazid alone for 6 or 9 months
B) Rifapentine plus isoniazid for 1 month
C) Isoniazid plus rifampin for 3 months
D) Rifampin alone for 4 months
Answer:
A) Isoniazid alone for 6 or 9 months
Rationale:
Isoniazid monotherapy for 6 or 9 months is recommended for both adults and children, with dosing adjustments based on age and weight. Other regimens, such as rifapentine plus isoniazid for 1 month, are not recommended for children under 13 years.
What is the recommended dose of rifampin for adults undergoing a 4-month tuberculosis preventive treatment?
A) 5 mg/kg per day
B) 10 mg/kg per day
C) 15 mg/kg weekly
D) 600 mg daily
Answer:
B) 10 mg/kg per day
Rationale:
For adults, the recommended dose of rifampin monotherapy for 4 months is 10 mg/kg per day. This regimen is a shorter alternative to isoniazid monotherapy and is effective for preventing tuberculosis in patients who cannot tolerate isoniazid.
Which tuberculosis preventive regimen is given as a once-weekly treatment for 3 months?
A) Rifapentine plus isoniazid
B) Rifampin alone
C) Isoniazid alone
D) Isoniazid plus rifampin
Answer:
A) Rifapentine plus isoniazid
Rationale:
The rifapentine plus isoniazid regimen for 3 months is administered weekly and is an effective short-course alternative to isoniazid monotherapy. This regimen improves adherence due to its reduced duration and frequency.
