TB Flashcards
When can a false positive TB skin test occur?
When a patient has received the BCG vaccine
A TST is also called what?
A purified protein derivative test
Latent TB Tx
3 possible
- Isoniazid 300 mg max 900 for 9 months
- Rifampin 4 months
- INH + rifapentine q wk for 12 wks
What regimen is recommend for HIV, pregnant and children? and for what?
INH: 300 mg per day max 900 per dose
9 months for Latent TB
What latent TB regimen is not rec’d for HIV, children < 2 or pregnant women
INH and Rifapentine
How to you confirm the Dx of Active TB?
Skin test likely means active but need to confirm with a sputum culture AFB stain
Definitive With PCR slow growing
In the intensive phase how long is RIPE therapy
8 wks
What is the treatment and durtation for conuation phase
2 drugs for 4 months
INH and RIF if susceptible
Drugs that cause QT prolongation Abxs
FQs
Macrolides
Drugs that cover atypical organisms? 3
Azithro
Doxy
Quinolones
Community Associated MRSA SSTIs drugs 3
- Bactrim
- Doxy
- Minocycline
More Severe SSTIs needing IV abx or Hospitalization cover what 2 things? and what are the 3 main drugs?
- Cover MRSA and Streptococcus
- Vanc
- Linezolid
- Daptomycin
WHen should IV abxs be admin for surgical prophylaxis?
Cefazolin and Cefuroxime ( 1hour before surgery)
If using quinolones or Vanc 120 minytes before
Common Cold MCPs 2
Influenza 1
Pharyngitis 2
Sinusitis 7
- Resp Virus: Rhinovirus and coronavirus
- Infuenza
- Resp viruses and S. Pyrogenes
- Resp viruses, S. Pneumo, H. Flu, M. Mat, staphylococcus, anaerobes, and g (-) rods
First line tc for sinusitis?
Amox/clav
Treatmetn for Pharyngitis?
PCN, Amox
Second line tx for sinusitis failure of first
Oral 2nd or 3rg gen cephs + clinda, doxy or Resp FQ
Tx duration for pharyngitis?
10
5 days for azithro
What patients are at risk of IE during dental procedures? 4
- Prosthetic heart valve or heart valve repair with artificial material
- Hx of endo
- Heart transplant with abnormal heart valve function
- Certain congenital heart defects including heart/lung valve disease
Adult prophylaxis regimens for Pts at risk of IE during dental procedure?
3 options
- Oral: amox 2 g 30-60 min before procedure
- Cant take oral: Amp 2 g or cefazolin 1 g
- Can take oral but PCN allergy:
- Clindamycin 600
- Azithro or clarithromycin 500
Other drugs besides Ceftriaxone that can be used for primary or secondary prophylaxis of SBP?
- Bactrim
- Cipro
Mild to moderate Peritonitis and Cholangitis
What to cover? 6
- PEK
- Anaerobes
- Strepto
- +- enterococcus
Mild to Moderate Peritonitis and Cholangitis
5 possible regimens
- Cefoxitin
- Ertrapenem
- Moxi
- Cefazolin, cefuroxime or ceftriaxone + metro
- Cipro or Levo + metro
Severe ICU patients Peritonitis and Cholangitis
What pathogens to cover? 12
- PEK
- CAPES
- Pseudomonas
- Anaerobes
- Strepto
- +- enterococcus
Impetigo
Honey COmb Crust
First choice
If numerous lesions
- Mupirocin (Bactroban) ointment
- Cover MSSA if systemmic: Cephalexin (Keflex)
Cellulitis Non-purulent infections
Cephalexin 500 mg QID
Absess Perulent Infections
Treatment 2
Commly caused by CA-MRSA
Bactrim
Doxy
DM Foot infections
G (+) Pathogens
4
G (-) 5
- S. Aureus Including MRSA
- Group A Strepto
- Viridan group strep
- S. Epidermidis
- E. Coli
- Klebsiella
- Proteus
- Enterobacter
- Pseudomonas
DM foot infections
Anaerobic G(+) 2
Aaerobic G (-) 1
- Peptostrepto
- Clostridium Perfringes
- B. Fragilis
Duration of treatment of DM foot infections
4 total
- 7-14
- More severe: 2-4 wks
- Bone and joint: 4-6 wks
- Osteo longer