Cephs Flashcards
What ceph can have increased risk of bleeding and cause a disulfram reaction
- Cefotetan contains a NMTT side chain or which increases bleeding risk and can cause a disulfram rxn
What ceph does not need renal adjustments?
Ceftriaxone
What ceph is available in chewable?
Cefixime
What ceph covers some CRE bugs?
Ceftaz/avibactam
What PCN allergy should you not use cephs with?
Type 1 swelling, angioedema, anaphylaxis
Ceftriaxone contraindication?
Causes biliary sludging in neonates,
Conccurrent use of Calcium containing IV products in neonates <=28 days
What 4 cephs should be separated by 2 hours with antacids?
Cefditoren, cefuroxime, cefpodoxime, cefdinir
First gen cepha coverage?
Gram (+) cocci and preferred when using cephs for MSSA
1st gen cephs 2
Cefazolin, Cephalexin (Keflex)
Second gen cephs 1
Cefuroxime
3rd gen cephs 1
Cefdinir
3rd gen group 2: 1
Ceftazidime
4 gen cephs
Cefepime
5th gen cephs?
Ceftaroline (teflaro)
2nd gen cephs what two drugs and what is the added coverage
Cefotetan, cefoxitin
Added G (-) anaerobe coverage B. Fragalis
Cefuroxime coverage 7 total
Staph and more resistant strains of S. Pneumo
Plus HNPEK
3rd gen group 1 coverage and drugs
Ceftriaxone and Cefotaxime
- which cover more resistant strains of strep and
- veridans group strep,
- MSSA
- G (+) anaerobes mouth flora and more resitant strains of HNPEK
Ceftazidime coverage?
Not active against g(+) but is active against pseudomonas
Fourth gen drug and coverage?
Cefepime, broad g (-) bacteria HNPEK, CAPES and Pseudomonas
Only Beta-lactam that covers MRSA?
Ceftaroline
