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Step 1: Microbio > TB > Flashcards

TB Flashcards

1
Q

Rifampin mechanism and side effect

A

inhibits bacterial DNA-dependent RNA polymerase.

Side effects:
GI, rash, red-orange fluid, cytopenias

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2
Q

Isoniazid

A

Inhibits mycolic acid synthesis in cell wall

Side effect:
Neurotoxicity (give with vit. B6)
hepatoxic

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3
Q

Pyrazinamide

A

Unclear

Hepatotoxic, hyperuricemia

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4
Q

Ethambutol

A

Inhibits arabinosyl transferase polymerization of cell wall

Optic neuropathy (red-green color blindness)

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5
Q

Fungus ball after TB

A

Aspergillus - broom like on silver stain

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Step 1: Microbio (8 decks)

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