TB Flashcards
Risk Factors
History of TB
Known contact of TB
Born in country with high incidence
Foreign Travel
Immunosuppression
Symptoms
Cough (Haemoptysis)
Breathlessness
Fever
Night Sweats
Weight Loss
Pathophysiology
Mycoplasma tubercolosis causes region of central necrosis (Gohn Comlpex)
Involvement of hilar Lymphn nodes (Gohn Complex)
Reactivation due to immunosupression:
Cavitations
Disseminaiton to distal organs
Systemic milliary TB.
Investigations
TB Skin Test
Inteferron Gamma Test
Acid Fast Stain
TB Culture/ PCR x3
Bronchoalveolar lavage (If unable to obtain sputum)
CXR
Routine Bloods
CT Chest
Treatment
Isolation
Notification
Contact tracing
Drug Treatment under DOT
Drug treatment
Isoniazid (6m)
Rifampicin (6m)
Pyranizamide (2m)
Ethambutol (2m)
Pyridoxine
Side effects
Isoniazid - Hepatitis, Rash, Peripheral Neuropathy
Rifampicin - Hepatitis Rash, Red urine
Ethambutol - Retrobulbar Neuritis
Pyranizamide - Hepatitis, Rash, Vomiting