Taste and smell Flashcards

1
Q

How are chemoreceptors of taste and smell stimulated?

A

By binding to particular chemicals

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2
Q

What can be influenced by the stimulation of taste and smell receptors?

A

The flow of digestive juice and enzymes

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3
Q

Where are sensory receptor cells of taste mainly located?

A

Packaged in taste buds

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4
Q

What is the average life span of taste receptor cells?

A

~10 days

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5
Q

How are taste receptor cells replaced?

A

By basal cells within the taste buds

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6
Q

What cells do taste receptor cells synapse with?

A

Afferent nerve fibres

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7
Q

What are the four types of papillae?

A

Filliform - most numerous
Fungiform
Vallate
Foliate

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8
Q

What is the only type of papillae that does not contain taste buds?

A

Filliform taste buds

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9
Q

What is a tastant?

A

A taste provoking chemical

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10
Q

What does the binding of tastants to receptor cells troduce?

A

A depolarising receptor potential

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11
Q

Where in the brain are taste signals conveyed to?

A

Cortical gustatory areas

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12
Q

What 3 cranial nerves are involved in the transmission of taste signals to the brainstem?

A

CN VII - chorda tympani
CN IX
CN X

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13
Q

What does the chorda tympani branch of CN VII innervate in relation to taste?

A

Anterior 2/3rds of tongue

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14
Q

What does CN IX innervate in relation to tase?

A

Posterior 1/3rd of tongue

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15
Q

What does CN X innervate in relation to taste?

A

Areas other than the tongue, such as the Epiglottis and Pharynx

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16
Q

What are the 5 primary tastes we can detect?

A

Bitter taste - alkaloids etc
Sour taste - H+
Salty taste - NaCL
Sweet taste - glucose
Umami - amino acids (glutamate)

17
Q

What is ageusia?

A

The loss of taste function

18
Q

What can cause ageusia?

A

Nerve damage
Local inflammation
Endocrine disorders

19
Q

What is hypogeusia?

A

A reduced taste function

20
Q

What can cause hypoguesia?

A

Drugs / medications
Chemotherapy

21
Q

What is dysgeusia?

A

A distortion of taste function

22
Q

What cranial nerve is responsible for the main olfactory system?

23
Q

What cranial nerve is responsible for the trigeminal somatosensory system?

24
Q

What cranial nerve mediates common odours?

25
What cranial nerve is responsible for irritation / burning / tickling of the nose?
CN V
26
What must a substance be in order to be able to be smelt?
Sufficiently volatile Sufficiently water soluble
27
How does sniffing increase the effectiveness of smell?
Draws more air current upwards within the nasal cavity to reach the olfactory mucosa which lies above the normal path of air flow
28
What type of epithelium is olfactory neuroepithelium?
Pseudostratified columnar epithelium
29
Where is mucus secreted from?
Duct cells of Bowmans glands
30
What is anosmia?
The inability to smell
31
What is hyposmia?
A reduced ability to smell
32
What is dysosmia?
An altered sense of smell
33
What is phantosmia?
A smell perceived in the absence of a stimulus (olfactory hallucination)
34
Give some causes of conductive loss of smell?
Nasal polyps Rhinitis Nasal mass
35
Give some causes of sensorineural loss of smell?
Viral causes - cold, covid Head trauma Neurological - Parkinson's Brain tumours Medications
36
How can smell be assessed in clinic?
Scratch and sniff tests
37
What should be done if there is no obvious cause for loss of smell?
Brain imaging
38
What are the main social impacts of poor / no smell?
Concern - safety, hygiene Loss of libido Career - chef, fire fighter etc.