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PPM 2 > Tabletting > Flashcards

Tabletting Flashcards

1
Q

Advantages of direct compression

A
  • Increase stability eliminates heat and moisture
  • Efficient and economical
  • Fewer exceipents
  • Batch to batch variable
  • Increase dissolution rate of particles
  • No ageing effect
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2
Q

Disadvantage of direct compression

A
  • Powder flowability and compressibility
  • Not suitable for high dose drug
  • Expensive equipment
  • Problematic compression process.
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3
Q

Three types of fillers

A
  • Lactose
  • Cellulose
  • Starch and derivatives
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4
Q

Lactose

A
  • Advantages: Dissolves readily in water/ nice taste/ non hygroscopic/ non reactive/ good compatibility
  • Disadvantages: Lactose intollerant patients
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5
Q

Celluslose

A

-Advanatges: Bicompactible/ inert/ high dilution potential

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PPM 2 (10 decks)

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