Capsules

Question 1

Schematic filing of hard gelatine capsules

Answer 1

1) Concentration of gelatin prepared in hot demineralised water
2) Pins mounted on metal pars are dipped in gelatin solution
3) Removed with a film of gelatin
- rotated
- passed through drying kins
- stripped of pins and cut to size
- two halves are joined together

Question 2

Powder filling : Dependent

Answer 2

Uses the capsule body directly to measure the powder

• slow
• dependent on operating skills and uniformity of dosing
• dependent on powder flow and uniformity of filling

Question 3

Powder filling : Independent

Answer 3

A plug of material is formed which is transferred to body dose is determined by volume of plug in dosator adjusted by the moving position of the piston

• Uses a dosator
• Tube containg a variable volume chamber at the bottom and piston at the top
• Used in large scale

Question 4

Powder filling of hard gelatine capsules

Answer 4

Diluents - Aids flow and compression
Glidents - Decrease interparticulate adhesion
Lubricants - Decreased adhesion to metals

Question 5

SGC shell has…

Answer 5

Gelatin/Plasticizer/Water/Preservatives, flavours, colorants,