tablets

Question 1

what are tablets

Answer 1

Solid dosage forms of medicinal substances (usually prepared with the aid of suitable pharmaceutical adjuncts)

Question 2

tablets can serve as a source of drug for

Answer 2

extemporaneous compounding of capsules, powders, ointments, paste, suspensions, etc. (not all pharmacies will have stock of every drug in powder form)

Question 3

tablets are preferred as the source of drug during

Answer 3

extemporaneous compounding (rather than the drug as pure powder)
- Especially when a small amount of the drug is needed for compounding a prescription because preparation of an aliquot mixture is avoided

Question 4

advantages of tablet dosage forms

Answer 4

pt, pharmacist, prescriber, and manufacturer prefers
- easy compliance and accuracy
-wide range of dosage strength
-helps mask bitter taste
-durable
-convenient and cheap

Question 5

Composition of A Tablet Dosage Form

Answer 5

• Active ingredient
• Diluent
• Binder
• Disintegrants
• Lubricant, antiadherent, and glidant
• Colorants
• Flavoring agents
• Sweeteners

Question 6

Oral tablets for ingestion

Answer 6

Compressed tablets or Standard compressed tablets
– Multiple compressed tablets(Layered tablets and Compression-coated tablets)
– Repeat-action tablets
– Delayed-action tablets
– Enteric-coated tablets
– Sugar-coated tablets
– Film-coated tablets
– Chewable tablets

Question 7

Tablets used in the oral cavity

Answer 7

Buccal tablets
– Sublingual tablets
– Troches and lozenges
– Orally dissolving tablets

Question 8

Tablets administered by other routes

Answer 8

implantation or vaginal tablets

Question 9

Tablets used to prepare solutions

Answer 9

effervescent tablets

Question 10

Molded tablets (MT)

Answer 10

Tablet triturates (TT) – Hypodermic tablets (HT) – Dispensing tablets (DT)

Question 11

Effervescent Tablets are formulated to

Answer 11

contain the active ingredient along with citric acid monohydrate and/or tartaric acid and sodium bicarbonate

Question 12

when dissolved in water, citric acid reacts with sodium bicarbonate to produce

Answer 12

sodium citrate and carbon dioxide

Question 13

tartaric acid reacts with sodium bicarbonate to produce

Answer 13

sodium tartrate and carbon dioxide

Question 14

The liberation of carbon dioxide as a result of

Answer 14

acid-base reaction between citric and/or tartaric acid and sodium bicarbonate

Question 15

USP Classification of Tablets

Answer 15

immediate release or modified release

Question 16

modified release tablets (MRT)

Answer 16

delayed release or extended release, continuous release, depot, gradual release, repository, slowly acting, etc

Question 17

Instances of Crushing a Solid Dosage Form

Answer 17

• Patient may be unable to swallow the solid dosage form but may find it convenient to take a liquid dosage form
• Patient may not want to swallow a tablet or a capsule due to psychological reasons
• Mixing of powdered medication with food or drink may make the drug more palatable
• Patient may have nasogastric tubes which do not permit administration of tablets or capsules
• Patient does not like to take the medication
  – Mixing the drug with food or a beverage may be the only way of making the patient take the drug
• An oral solution for a particular medication may not be available from the manufacturer or readily prepared by pharmacy

Question 18

Oral Dosage Forms That Should Not Be Crushed

Answer 18

• Enteric-coated products
• Extended-release products
• Unpleasant tasting medication
• Effervescent tablets
• Sublingual tablets

Question 19

what are some misc drugs that can’t be crushed

Answer 19

dosage forms that irritate muosa, have dyes (stain teeth and mucosal tissue), can be carcinogenic, and products made to change release characteristics of the drug from the dosage form